Impact of β-amyloid on the tau pathology in tau transgenic mouse and tissue culture models

Jürgen Götz, Della C. David, Lars M. Ittner

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Dementia is a generic term that describes chronic or progressive dysfunction of cortical and subcortical functions that result in complex cognitive decline. These cognitive changes are commonly accompanied by disturbances of mood, behavior, and personality. In developed countries with an increasingly aging population, the prevalence of dementia is currently at around 1.5% at 65 years of age, which doubles every 4 years and reaches about 30% at the age of 80.

Original languageEnglish
Title of host publicationAbeta peptide and Alzheimer's disease
Subtitle of host publicationcelebrating a century of research
EditorsColin J. Barrow, David H. Small
Place of PublicationLondon
PublisherSpringer, Springer Nature
Chapter12
Pages198-215
Number of pages18
ISBN (Electronic)9781846284403
ISBN (Print)1852339616, 9781852339616
DOIs
Publication statusPublished - 1 Dec 2007
Externally publishedYes

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