Impact of comorbidities on ischemic stroke outcomes in women

Cheryl D. Bushnell, Jeanne Lee, Pamela W. Duncan, L. Kristin Newby, Larry B. Goldstein

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

BACKGROUND AND PURPOSE-We assessed the association of prestroke comorbidities with long-term stroke outcomes among women with ischemic stroke. METHODS-Prestroke comorbid conditions in 133 women admitted with acute ischemic stroke were scored with the Charlson Index (CI). We assessed whether the CI and other specific conditions were associated with modified Rankin Score (mRS) at 90 days or more poststroke. RESULTS-After adjustment for initial NIHSS and age, higher CI was the sole factor independently associated with poorer 90 day mRS scores. When CI was excluded, coronary disease and diabetes were independently associated with poorer outcome. CONCLUSION-The extent of comorbidities as assessed by the CI is independently associated with 90-day mRS among women with ischemic stroke, but the individual comorbidities of CHD and DM were each associated with functional outcome.

Original languageEnglish
Pages (from-to)2138-2140
Number of pages3
JournalStroke
Volume39
Issue number7
DOIs
Publication statusPublished - 1 Jul 2008
Externally publishedYes

Keywords

  • Acute stroke
  • Comorbidities
  • Outcome
  • Stroke recovery
  • Women and minorities

Fingerprint Dive into the research topics of 'Impact of comorbidities on ischemic stroke outcomes in women'. Together they form a unique fingerprint.

  • Cite this

    Bushnell, C. D., Lee, J., Duncan, P. W., Newby, L. K., & Goldstein, L. B. (2008). Impact of comorbidities on ischemic stroke outcomes in women. Stroke, 39(7), 2138-2140. https://doi.org/10.1161/STROKEAHA.107.509281