Impact of hybrid procedure on P wave duration for atrial fibrillation ablation

Narendra Kumar*, Pietro Bonizzi, Laurent Pison, Kevin Phan, Theo Lankveld, Bart Maessen, Mark La Meir, Sandro Gelsomino, Jos Maessen, Harry Crijns

*Corresponding author for this work

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Aim: Hybrid procedure (HP) involves epicardial isolation of pulmonary vein and posterior wall of left atrium, and endocardial checking of lesions and touchups (if needed). We aimed at observing the effect of hybrid procedure on P wave duration (PWD), calculated automatically from surface ECG leads at start and end of HP, and also for relationship to atrial fibrillation (AF) recurrence at 9 months.

Methods: Forty-one patients (32 male; mean age, 58.4 ± 9.5 years) underwent HP, as first ever ablation. A new automated method was used for P wave segmentation and PWD estimation from recognizable P waves in ECG lead I or II before and after HP, based on fitting of each P wave by means of two Gaussian functions.

Results: Overall, PWD was significantly decreased after procedure (104.4 ± 25.1 ms vs. 84.7 ± 23.8 ms, p = 0.0151), especially in persistent AF patients (122.4 ± 32.2 ms vs. 85.6 ± 24.5 ms, p = 0.02). PWD preprocedure was significantly higher in persistent than in paroxysmal patients (122.4 ± 32.2 ms vs. 92.5 ± 17.9 ms, p = 0.0383). PWD was significantly decreased after procedure in prior electrical cardioverted patients (106.7 ± 30.5 ms vs. 84.7 ± 23.1 ms, p = 0.0353). After 9-month follow-up of 40 patients, HP-induced PWD decrease was significant for the 12 persistent patients without recurrence (122.4.1 ± 35.3 ms vs. 85.6 ± 22.0 ms, p = 0.0210).

Conclusion: Preprocedure PWD was higher for persistent than paroxysmal patients. HP reduced PWD significantly. Nine-month follow-up suggests that HP is successful in restoring and maintaining sinus rhythm. To individualize AF therapy, AF type-based selection of patients may be possible before procedure. Automated analysis of PWD from surface ECG is possible.

Original languageEnglish
Pages (from-to)91-99
Number of pages9
JournalJournal of Interventional Cardiac Electrophysiology
Volume42
Issue number2
DOIs
Publication statusPublished - Mar 2015

Bibliographical note

An erratum for this article exists and can be found in the Journal of Interventional Vardiac Electrophysiology, vol. 42(2), p. 171. DOI: 10.1007/s10840-015-9987-2

Keywords

  • atrial fibrillation
  • electrocardiography
  • hybrid procedure
  • P wave duration
  • radiofrequency
  • surgical ablation

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