This review articles showcases some of the work done on biomedical applications using capacitive-based microsensors. The sensors were interdigitated in nature, operating on capacitive principle. The first type of sensors are the MEMS-based ones that were used for detecting different concentrations of CTx-1 in serum, which is an essential biomarker for early detection of osteoporosis. The second type of sensors are the flexible, strain-induced ones, which were used for the detection of human motion via movement of different body parts. These sensor prototypes provide a solid podium for employing micro-sensing technology for detecting biomedical parameters.