Implementation of genomics into clinical practice: a service level view

Research output: Contribution to conferenceAbstractpeer-review


The potential health benefits of genomic medicine have been promised for many years but have been slow to be realised in patient care. Translating evidence based findings across the boundaries of the research setting into clinical practice is challenging. In this regard genomic medicine is no different to other clinical fields. For many clinical arenas, however, genomics has the potential to be a disruptive evidence based health care practice and as such will need support from the service level personnel to, for example, change policies and reallocate funding. If the potential benefits of genomic medicine are to be realised, changes in clinician practice need to be supported by the organisation. The focus of implementation research in this area has largely centred on clinical practice, yet this disregards the essential role the organisation and service level personnel play in the manifestation of new frontline clinical services. This paper has two aims: one, to review the literature to identify what organisational barriers are known to hinder implementation of genomics; and two, to set out a theory informed research plan to explore organisational factors that influence the uptake of clinical genomics. The review discovered a paucity of studies in this area, supporting the need for further research. Themes from the papers indicate the importance of the operational infrastructure, the need for multilevel involvement, and the challenge of the rapidly evolving genomic evidence base. The research plan builds on these findings and, using the Translation Science to Population Impact (TSci Impact) framework, outlines a research protocol to investigate perceptions of service level personnel in the early phases of implementation of clinical genomics. Initial findings will be available early 2018.
Original languageEnglish
Number of pages1
Publication statusPublished - 2018
EventInternational Organizational Behaviour in Healthcare Conference - Montreal, Canada
Duration: 13 May 201816 May 2018


ConferenceInternational Organizational Behaviour in Healthcare Conference


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