TY - JOUR
T1 - Improving the echocardiographic assessment of pulmonary pressure using the tricuspid regurgitant signal
T2 - the “chin” vs the “beard”
AU - Kyranis, Stephen J.
AU - Latona, Jilani
AU - Platts, David
AU - Kelly, Natalie
AU - Savage, Michael
AU - Brown, Martin
AU - Hamilton-Craig, Christian
AU - Scalia, Gregory M.
AU - Burstow, Darryl
PY - 2018/8
Y1 - 2018/8
N2 - Aim: Transthoracic echocardiography (TTE) is a fundamental investigation for the noninvasive assessment of pulmonary hemodynamics and right heart function. The aim of this study was to assess the correlation and agreement of Doppler calculation of right ventricular systolic pressure (RVSP) and pulmonary vascular resistance (PVR) using “chin” and “beard” measurements of tricuspid regurgitant velocity (TRV
max), with invasive pulmonary artery systolic pressure (PASP) and PVR. Methods: One hundred patients undergoing right heart catheterisation (RHC) and near simultaneous transthoracic echocardiography were studied. TRV
max was recorded for “chin” measurement (distinct peak TRV
max signal) and where available (63 patients), “beard” measurement (higher indistinct peak TRV
max signal). Results: Measurable TRV signal was obtained in 96 patients. Mean RVSP
chin 54.7 ± 22.7 mm Hg and RVSP
beard 68.6 = 23 ± 26.3 mm Hg (P <.001). There was strong correlation between both RVSP
chin and RVSP
beard with invasive PASP (Pearson’s r =.9, R
2 = 0.82, P <.001-r =.88, R =.78, P <.001, respectively.). Bland-Altman analysis for RVSP
chin and RVSP
beard showed a mean bias of −0.5 mm Hg (95% limits of agreement −21.4 to 20.5 mm Hg) and −10.7 (95% LOA −35.5 to 14.2 mm Hg), respectively. Receiver operator characteristics of TRV
max “chin” and “beard” for diagnosis of pulmonary hypertension was assessed with optimal cut-offs being 2.8 m/s (sensitivity 93%, specificity 87%) and 3.2 m/s (sensitivity 91%, specificity 82%), respectively. There was similar correlation between PVR
chin and PVR
beard (r =.87, R
2 = 0.75, P <.001 and r =.86, R
2 = 0.74, P <.001, respectively). At higher PVR, there was overestimation of calculated PVR using PVR
beard. Conclusion: The accuracy of noninvasive measurement of right heart pressures is increased using the “chin” in estimation of both RVSP and PVR.
AB - Aim: Transthoracic echocardiography (TTE) is a fundamental investigation for the noninvasive assessment of pulmonary hemodynamics and right heart function. The aim of this study was to assess the correlation and agreement of Doppler calculation of right ventricular systolic pressure (RVSP) and pulmonary vascular resistance (PVR) using “chin” and “beard” measurements of tricuspid regurgitant velocity (TRV
max), with invasive pulmonary artery systolic pressure (PASP) and PVR. Methods: One hundred patients undergoing right heart catheterisation (RHC) and near simultaneous transthoracic echocardiography were studied. TRV
max was recorded for “chin” measurement (distinct peak TRV
max signal) and where available (63 patients), “beard” measurement (higher indistinct peak TRV
max signal). Results: Measurable TRV signal was obtained in 96 patients. Mean RVSP
chin 54.7 ± 22.7 mm Hg and RVSP
beard 68.6 = 23 ± 26.3 mm Hg (P <.001). There was strong correlation between both RVSP
chin and RVSP
beard with invasive PASP (Pearson’s r =.9, R
2 = 0.82, P <.001-r =.88, R =.78, P <.001, respectively.). Bland-Altman analysis for RVSP
chin and RVSP
beard showed a mean bias of −0.5 mm Hg (95% limits of agreement −21.4 to 20.5 mm Hg) and −10.7 (95% LOA −35.5 to 14.2 mm Hg), respectively. Receiver operator characteristics of TRV
max “chin” and “beard” for diagnosis of pulmonary hypertension was assessed with optimal cut-offs being 2.8 m/s (sensitivity 93%, specificity 87%) and 3.2 m/s (sensitivity 91%, specificity 82%), respectively. There was similar correlation between PVR
chin and PVR
beard (r =.87, R
2 = 0.75, P <.001 and r =.86, R
2 = 0.74, P <.001, respectively). At higher PVR, there was overestimation of calculated PVR using PVR
beard. Conclusion: The accuracy of noninvasive measurement of right heart pressures is increased using the “chin” in estimation of both RVSP and PVR.
KW - echocardiography
KW - pulmonary hypertension
KW - tricuspid regurgitant velocity
KW - TRV
UR - http://www.scopus.com/inward/record.url?scp=85054567226&partnerID=8YFLogxK
U2 - 10.1111/echo.13893
DO - 10.1111/echo.13893
M3 - Article
C2 - 29676489
SN - 0742-2822
VL - 35
SP - 1085
EP - 1096
JO - Echocardiography
JF - Echocardiography
IS - 8
ER -