In Vitro neuronal depolarization and increased synaptic activity induced by infrared neural stimulation

Blake Entwisle*, Simon McMullan, Phillip Bokiniec, Simon Grosss, Roger Chung, Michael Withford

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference proceeding contributionpeer-review

Abstract

Neuronal responses to infrared neural stimulation (INS) are explored at the single cell level. We examined membrane and synaptic responses of solitary tract neurons prepared from the Sprague-Dawley rat. Neurons were stimulated using a 1890 nm laser with light delivered via single-mode fiber. We show that infrared radiation increased spontaneous synaptic event frequency, and evoked steady-state currents. The magnitude of the responses was proportional to laser output.

Original languageEnglish
Title of host publicationFrontiers in Optics 2016
Subtitle of host publicationproceedings
Place of PublicationWashington, D.C.
PublisherOSA - The Optical Society
Number of pages2
ISBN (Print)9781943580194
DOIs
Publication statusPublished - 2016
EventFrontiers in Optics, FiO 2016 - Rochester, United States
Duration: 17 Oct 201621 Oct 2016

Other

OtherFrontiers in Optics, FiO 2016
CountryUnited States
CityRochester
Period17/10/1621/10/16

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