Induced neural lineage cells as repair kits

so close, yet so far away

Fahimeh Mirakhori, Bahman Zeynali, Ghasem Hosseini Salekdeh, Hossein Baharvand*

*Corresponding author for this work

Research output: Contribution to journalReview article

14 Citations (Scopus)

Abstract

Transdifferentiation or direct reprogramming of somatic cells into neural lineage cells has provided an invaluable new tool to advance the regenerative neural medicine. Here, we provide an overview of the various strategies currently available for producing of induced neural lineage cells in vitro as well as the direct reprogramming of neural cells in vivo. We also discussing some of the challenges faced in harnessing the potential of induced neural lineage cells for biomedical applications.

Original languageEnglish
Pages (from-to)728-742
Number of pages15
JournalJournal of Cellular Physiology
Volume229
Issue number6
DOIs
Publication statusPublished - Jun 2014
Externally publishedYes

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