Induced neural lineage cells as repair kits: so close, yet so far away

Fahimeh Mirakhori; Bahman Zeynali; Ghasem Hosseini Salekdeh; Hossein Baharvand

doi:10.1002/jcp.24509

Induced neural lineage cells as repair kits: so close, yet so far away

Fahimeh Mirakhori, Bahman Zeynali, Ghasem Hosseini Salekdeh, Hossein Baharvand^*

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

14 Citations (Scopus)

Abstract

Transdifferentiation or direct reprogramming of somatic cells into neural lineage cells has provided an invaluable new tool to advance the regenerative neural medicine. Here, we provide an overview of the various strategies currently available for producing of induced neural lineage cells in vitro as well as the direct reprogramming of neural cells in vivo. We also discussing some of the challenges faced in harnessing the potential of induced neural lineage cells for biomedical applications.

Original language	English
Pages (from-to)	728-742
Number of pages	15
Journal	Journal of Cellular Physiology
Volume	229
Issue number	6
DOIs	https://doi.org/10.1002/jcp.24509
Publication status	Published - Jun 2014
Externally published	Yes

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10.1002/jcp.24509

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abstract = "Transdifferentiation or direct reprogramming of somatic cells into neural lineage cells has provided an invaluable new tool to advance the regenerative neural medicine. Here, we provide an overview of the various strategies currently available for producing of induced neural lineage cells in vitro as well as the direct reprogramming of neural cells in vivo. We also discussing some of the challenges faced in harnessing the potential of induced neural lineage cells for biomedical applications.",

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AU - Zeynali, Bahman

AU - Salekdeh, Ghasem Hosseini

AU - Baharvand, Hossein

PY - 2014/6

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AB - Transdifferentiation or direct reprogramming of somatic cells into neural lineage cells has provided an invaluable new tool to advance the regenerative neural medicine. Here, we provide an overview of the various strategies currently available for producing of induced neural lineage cells in vitro as well as the direct reprogramming of neural cells in vivo. We also discussing some of the challenges faced in harnessing the potential of induced neural lineage cells for biomedical applications.

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M3 - Review article

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Induced neural lineage cells as repair kits: so close, yet so far away

Abstract

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