Induction, isolation and testing of stable Trichoderma reesei mutants with improved production of solubilizing cellulase

M. J. Bailey*, K. M H Nevalainen

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

243 Citations (Scopus)

Abstract

A mutant strain of the fungus Trichoderma reesei giving high cellulase production but having poor stability has been further mutagenized to produce strains in which good production properties were retained and stability was greatly improved. The increase in the production of some other extracellular enzymes by the mutants was even greater than the increase in cellulase (EC 3.2.1.4) and exo-cellobiohydrolase (EC 3.2.1.91) production. The new strains were all tested in laboratory fermenter cultivations and one has also been used for pilot-scale cellulase production.

Original languageEnglish
Pages (from-to)153-157
Number of pages5
JournalEnzyme and Microbial Technology
Volume3
Issue number2
DOIs
Publication statusPublished - 1981
Externally publishedYes

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