Induction, isolation and testing of stable Trichoderma reesei mutants with improved production of solubilizing cellulase

M. J. Bailey; K. M H Nevalainen

doi:10.1016/0141-0229(81)90076-4

Induction, isolation and testing of stable Trichoderma reesei mutants with improved production of solubilizing cellulase

M. J. Bailey^*, K. M H Nevalainen

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

260 Citations (Scopus)

Abstract

A mutant strain of the fungus Trichoderma reesei giving high cellulase production but having poor stability has been further mutagenized to produce strains in which good production properties were retained and stability was greatly improved. The increase in the production of some other extracellular enzymes by the mutants was even greater than the increase in cellulase (EC 3.2.1.4) and exo-cellobiohydrolase (EC 3.2.1.91) production. The new strains were all tested in laboratory fermenter cultivations and one has also been used for pilot-scale cellulase production.

Original language	English
Pages (from-to)	153-157
Number of pages	5
Journal	Enzyme and Microbial Technology
Volume	3
Issue number	2
DOIs	https://doi.org/10.1016/0141-0229(81)90076-4
Publication status	Published - 1981
Externally published	Yes

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abstract = "A mutant strain of the fungus Trichoderma reesei giving high cellulase production but having poor stability has been further mutagenized to produce strains in which good production properties were retained and stability was greatly improved. The increase in the production of some other extracellular enzymes by the mutants was even greater than the increase in cellulase (EC 3.2.1.4) and exo-cellobiohydrolase (EC 3.2.1.91) production. The new strains were all tested in laboratory fermenter cultivations and one has also been used for pilot-scale cellulase production.",

author = "Bailey, {M. J.} and Nevalainen, {K. M H}",

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AU - Bailey, M. J.

AU - Nevalainen, K. M H

PY - 1981

Y1 - 1981

N2 - A mutant strain of the fungus Trichoderma reesei giving high cellulase production but having poor stability has been further mutagenized to produce strains in which good production properties were retained and stability was greatly improved. The increase in the production of some other extracellular enzymes by the mutants was even greater than the increase in cellulase (EC 3.2.1.4) and exo-cellobiohydrolase (EC 3.2.1.91) production. The new strains were all tested in laboratory fermenter cultivations and one has also been used for pilot-scale cellulase production.

AB - A mutant strain of the fungus Trichoderma reesei giving high cellulase production but having poor stability has been further mutagenized to produce strains in which good production properties were retained and stability was greatly improved. The increase in the production of some other extracellular enzymes by the mutants was even greater than the increase in cellulase (EC 3.2.1.4) and exo-cellobiohydrolase (EC 3.2.1.91) production. The new strains were all tested in laboratory fermenter cultivations and one has also been used for pilot-scale cellulase production.

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IS - 2

ER -

Induction, isolation and testing of stable Trichoderma reesei mutants with improved production of solubilizing cellulase

Abstract

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