Respiratory motion (R M) represents a major factor of image degradation with potential impact on the detection of embolic lesions in lung perfusion scintigraphy. The aim was to investigate the influence of RM on the contrast of pulmonary lesions through a simulation study with a virtual phantom. Using a N-CAT phantom, a SPECT lung perfusion model was generated; the model was reconstructed producing three sets of tomographic slices and image reprojection under different conditions: without RM, RM simulation with 2 cm diaphragmatic displacement, and RM simulation with 4 cm diaphragmatic displacement. Seven "cold" lesions were placed in the model resembling a typical pulmonary embolism (PE) situation in superior, medial and basal locations and image contrast was calculated. Results showed a decrease in lesion contrast proportional to the degree of RM, which was more pronounced for basal lesions. Motion correction could improve the detectability of some perfusion defects, especially those in basal locations, thus incrementing the sensitivity of the technique for the diagnosis of PE.
|Translated title of the contribution||Influence of respiratory movement on the contrast of lesions in lung perfusion studies: simulation using a virtual phantom|
|Number of pages||6|
|Journal||ALASBIMN Journal: revista de medicina nuclear|
|Publication status||Published - 2010|
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- lung perfusion
- respiratory motion