Initial evaluation of a commercial EPID modified to a novel direct-detection configuration for radiotherapy dosimetry

Philip Vial, Peter B. Greer, Lyn Oliver, Clive Baldock

Research output: Contribution to journalArticlepeer-review

47 Citations (Scopus)


Electronic portal imaging devices (EPIDs) integrated with medical linear accelerators utilize an indirect-detection EPID configuration (ID-EPID). Amorphous silicon ID-EPIDs provide high quality low dose images for verification of radiotherapy treatments but they have limitations as dosimeters. The standard ID-EPID configuration includes a high atomic number phosphor scintillator screen, a 1 mm copper layer, and other nonwater equivalent materials covering the detector. This configuration leads to marked differences in the response of an ID-EPID compared to standard radiotherapy dosimeters such as ion chambers in water. In this study the phosphor and copper were removed from a standard commercial EPID to modify the configuration to a direct-detection EPID (DD-EPID). Using solid water as the buildup and backscatter for the detector, dosimetric measurements were performed on the DD-EPID and compared to standard dose-in-water data for 6 and 18 MV photons. The sensitivity of the DD-EPID was approximately eight times less than the ID-EPID but the signal was sufficient to produce accurate and reproducible beam profile measurements for open beams and an intensity-modulated beam. Due to the lower signal levels it was found necessary to ensure that the dark field correction (no radiation) DD-EPID signal was stable or updated frequently. The linearity of dose response was comparable to the ID-EPID but with a greater under-response at low doses. DD-EPID measurements of field size output factors and beam profiles at the depth of maximum dose (dmax), and tissue-maximum ratios between the depths of 0.5 and 10 cm, were in close agreement with dose in water measurements. At depths beyond dmax the DD-EPID showed a greater change in response to field size than ionisation chamber measurements and the beam penumbrae were broader compared to diode scans. The modified DD-EPID configuration studied here has the potential to improve the performance of EPIDs for dose verification of radiotherapy treatments.
Original languageEnglish
Pages (from-to)4362-4374
Number of pages13
JournalMedical Physics
Issue number10
Publication statusPublished - 2008
Externally publishedYes


  • Amorphous silicon
  • Dosimetry
  • EPID
  • Flat panel dosimeter
  • Quality assurance


Dive into the research topics of 'Initial evaluation of a commercial EPID modified to a novel direct-detection configuration for radiotherapy dosimetry'. Together they form a unique fingerprint.

Cite this