Insight into autonomic nervous system control of heart rate in the rat using analysis of heart rate variability and baroreflex sensitivity

Cara M. Hildreth; Ann K. Goodchild; Jacqueline K. Phillips

doi:10.1007/978-1-62703-233-9_12

Insight into autonomic nervous system control of heart rate in the rat using analysis of heart rate variability and baroreflex sensitivity

Cara M. Hildreth^*, Ann K. Goodchild, Jacqueline K. Phillips

^*Corresponding author for this work

Macquarie University BioFocus Research Centre

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

6 Citations (Scopus)

Abstract

Heart rate variability and baroreflex sensitivity are two readily accessible methods available to assess control of heart rate by the autonomic nervous system. Heart rate variability can provide information regarding neural (parasympathetic, sympathetic, reflex) and nonneural (hormones, thermoregulation) control of heart rate. Baroreflex sensitivity provides information on how effective the autonomic nervous system is in rapidly changing heart rate in response to changes in blood pressure. Methods are presented on how to calculate heart rate variability using frequency domain analysis and how to calculate baroreflex sensitivity using the sequence method and α-coefficient method of analysis. Data is presented from a variety of rat strains (control, hypertensive, kidney disease, depressed) to indicate the utility of these methods for comparing autonomic regulation of the heart in both anaesthetised animals via intra-arterial recordings and conscious animals using telemetry.

Original language	English
Title of host publication	Stimulation and Inhibition of Neurons
Editors	Paul M. Pilowsky, Melissa M. J. Farnham, Angelina Y. Fong
Place of Publication	New York
Publisher	Humana Press
Pages	203-223
Number of pages	21
ISBN (Electronic)	9781627032339
ISBN (Print)	9781627032322
DOIs	https://doi.org/10.1007/978-1-62703-233-9_12
Publication status	Published - 2013

Publication series

Name	Neuromethods
Volume	78
ISSN (Print)	0893-2336
ISSN (Electronic)	1940-6045

Keywords

α-Coefficient
Baroreflex sensitivity
Frequency domain analysis
Heart rate variability
Radiotelemetry
Sequence method

Access to Document

10.1007/978-1-62703-233-9_12

Cite this

Hildreth, C. M., Goodchild, A. K., & Phillips, J. K. (2013). Insight into autonomic nervous system control of heart rate in the rat using analysis of heart rate variability and baroreflex sensitivity. In P. M. Pilowsky, M. M. J. Farnham, & A. Y. Fong (Eds.), Stimulation and Inhibition of Neurons (pp. 203-223). (Neuromethods; Vol. 78). Humana Press. https://doi.org/10.1007/978-1-62703-233-9_12

Hildreth, Cara M. ; Goodchild, Ann K. ; Phillips, Jacqueline K. / Insight into autonomic nervous system control of heart rate in the rat using analysis of heart rate variability and baroreflex sensitivity. Stimulation and Inhibition of Neurons. editor / Paul M. Pilowsky ; Melissa M. J. Farnham ; Angelina Y. Fong. New York : Humana Press, 2013. pp. 203-223 (Neuromethods).

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abstract = "Heart rate variability and baroreflex sensitivity are two readily accessible methods available to assess control of heart rate by the autonomic nervous system. Heart rate variability can provide information regarding neural (parasympathetic, sympathetic, reflex) and nonneural (hormones, thermoregulation) control of heart rate. Baroreflex sensitivity provides information on how effective the autonomic nervous system is in rapidly changing heart rate in response to changes in blood pressure. Methods are presented on how to calculate heart rate variability using frequency domain analysis and how to calculate baroreflex sensitivity using the sequence method and α-coefficient method of analysis. Data is presented from a variety of rat strains (control, hypertensive, kidney disease, depressed) to indicate the utility of these methods for comparing autonomic regulation of the heart in both anaesthetised animals via intra-arterial recordings and conscious animals using telemetry.",

keywords = "α-Coefficient, Baroreflex sensitivity, Frequency domain analysis, Heart rate variability, Radiotelemetry, Sequence method",

author = "Hildreth, {Cara M.} and Goodchild, {Ann K.} and Phillips, {Jacqueline K.}",

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Hildreth, CM , Goodchild, AK & Phillips, JK 2013, Insight into autonomic nervous system control of heart rate in the rat using analysis of heart rate variability and baroreflex sensitivity. in PM Pilowsky, MMJ Farnham & AY Fong (eds), Stimulation and Inhibition of Neurons. Neuromethods, vol. 78, Humana Press, New York, pp. 203-223. https://doi.org/10.1007/978-1-62703-233-9_12

Insight into autonomic nervous system control of heart rate in the rat using analysis of heart rate variability and baroreflex sensitivity. / Hildreth, Cara M.; Goodchild, Ann K.; Phillips, Jacqueline K.
Stimulation and Inhibition of Neurons. ed. / Paul M. Pilowsky; Melissa M. J. Farnham; Angelina Y. Fong. New York: Humana Press, 2013. p. 203-223 (Neuromethods; Vol. 78).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

TY - CHAP

T1 - Insight into autonomic nervous system control of heart rate in the rat using analysis of heart rate variability and baroreflex sensitivity

AU - Hildreth, Cara M.

AU - Goodchild, Ann K.

AU - Phillips, Jacqueline K.

PY - 2013

Y1 - 2013

N2 - Heart rate variability and baroreflex sensitivity are two readily accessible methods available to assess control of heart rate by the autonomic nervous system. Heart rate variability can provide information regarding neural (parasympathetic, sympathetic, reflex) and nonneural (hormones, thermoregulation) control of heart rate. Baroreflex sensitivity provides information on how effective the autonomic nervous system is in rapidly changing heart rate in response to changes in blood pressure. Methods are presented on how to calculate heart rate variability using frequency domain analysis and how to calculate baroreflex sensitivity using the sequence method and α-coefficient method of analysis. Data is presented from a variety of rat strains (control, hypertensive, kidney disease, depressed) to indicate the utility of these methods for comparing autonomic regulation of the heart in both anaesthetised animals via intra-arterial recordings and conscious animals using telemetry.

AB - Heart rate variability and baroreflex sensitivity are two readily accessible methods available to assess control of heart rate by the autonomic nervous system. Heart rate variability can provide information regarding neural (parasympathetic, sympathetic, reflex) and nonneural (hormones, thermoregulation) control of heart rate. Baroreflex sensitivity provides information on how effective the autonomic nervous system is in rapidly changing heart rate in response to changes in blood pressure. Methods are presented on how to calculate heart rate variability using frequency domain analysis and how to calculate baroreflex sensitivity using the sequence method and α-coefficient method of analysis. Data is presented from a variety of rat strains (control, hypertensive, kidney disease, depressed) to indicate the utility of these methods for comparing autonomic regulation of the heart in both anaesthetised animals via intra-arterial recordings and conscious animals using telemetry.

KW - α-Coefficient

KW - Baroreflex sensitivity

KW - Frequency domain analysis

KW - Heart rate variability

KW - Radiotelemetry

KW - Sequence method

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UR - http://purl.org/au-research/grants/nhmrc/1030301

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M3 - Chapter

AN - SCOPUS:84871839583

SN - 9781627032322

T3 - Neuromethods

SP - 203

EP - 223

BT - Stimulation and Inhibition of Neurons

A2 - Pilowsky, Paul M.

A2 - Farnham, Melissa M. J.

A2 - Fong, Angelina Y.

PB - Humana Press

CY - New York

ER -

Insight into autonomic nervous system control of heart rate in the rat using analysis of heart rate variability and baroreflex sensitivity

Abstract

Publication series

Keywords

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Reduced baroreceptor reflex control of heart rate in chronic renal failure

Cite this

Insight into autonomic nervous system control of heart rate in the rat using analysis of heart rate variability and baroreflex sensitivity

Abstract

Publication series

Keywords

Access to Document

Other files and links

Fingerprint

Projects

Reduced baroreceptor reflex control of heart rate in chronic renal failure

Cite this