Insights into etiological factors of pulmonary hypertension in cancer patients

Loma Al-Mansouri*, Firas Al-Obaidi

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

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Pulmonary hypertension is a rare vascular disease that can affect patients with or surviving malignancy resulting in significant morbidity and high mortality. Malignant diseases can lead to elevated pulmonary artery pressure through different mechanisms, either directly by structural obstruction of pulmonary vessels or indirectly through hypercoagulable state or treatment toxicity culminating in high pulmonary vascular resistance. The most common causes of cancer-related pulmonary hypertension are thromboembolic diseases, tumour emboli and treatment toxicity and less commonly intravascular tumours and malignant extrinsic compression.

Original languageEnglish
Pages (from-to)236-242
Number of pages7
Issue number4
Publication statusPublished - 29 Dec 2017

Bibliographical note

Copyright the Author(s) 2017. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.


  • Cancer
  • Cardiac toxicity
  • Chemotherapy
  • Pulmonary arterial hypertension
  • Pulmonary hypertension
  • Pulmonary veno-occlusive disease


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