Integrating genomics into healthcare: a global responsibility

Zornitza Stark, Lena Dolman, Teri A. Manolio, Brad Ozenberger, Sue L. Hill, Mark J. Caulfied, Yves Levy, David Glazer, Julia Wilson, Mark Lawler, Tiffany Boughtwood, Jeffrey Braithwaite, Peter Goodhand, Ewan Birney, Kathryn N. North*

*Corresponding author for this work

Research output: Contribution to journalComment/opinionpeer-review

200 Citations (Scopus)
16 Downloads (Pure)


Genomic sequencing is rapidly transitioning into clinical practice, and implementation into healthcare systems has been supported by substantial government investment, totaling over US$4 billion, in at least 14 countries. These national genomic-medicine initiatives are driving transformative change under real-life conditions while simultaneously addressing barriers to implementation and gathering evidence for wider adoption. We review the diversity of approaches and current progress made by national genomic-medicine initiatives in the UK, France, Australia, and US and provide a roadmap for sharing strategies, standards, and data internationally to accelerate implementation.

Original languageEnglish
Pages (from-to)13-20
Number of pages8
JournalAmerican Journal of Human Genetics
Issue number1
Publication statusPublished - 3 Jan 2019

Bibliographical note

Copyright American Society of Human Genetics 2018. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.


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