TY - JOUR
T1 - Intracerebral hemorrhage after thrombolytic therapy managed with ventricular drainage
AU - Al-Khawaja, Darweesh
AU - Eslick, Guy D.
AU - Fuller, Stephen J.
AU - Seex, Kevin
PY - 2007/9
Y1 - 2007/9
N2 - Intracerebral hemorrhage (ICH) after thrombolytic treatment for acute myocardial infarction (AMI) is a serious complication causing significant morbidity and mortality. Drainage of the haematoma by craniotomy is associated with poor outcome. We present a patient who received tissue plasminogen activator (t-PA) for acute myocardial infarction; he subsequently developed an ICH with ventricular system extension. The patient was managed by insertion of an external ventricular drain. The hemorrhage was successfully evacuated by insertion of the external ventricular drain. This was unexpected as ICH are usually viscous and difficult to aspirate in the acute phase. This suggests that ICHs following thrombolytic therapy remain liquid for up to 10 h. External ventricular drains can be used in the management of patients with ICH complicating thrombolytic therapy for management of acute myocardial infarction or ischemic stroke. This reduces the need for craniotomy and associated morbidity and mortality.
AB - Intracerebral hemorrhage (ICH) after thrombolytic treatment for acute myocardial infarction (AMI) is a serious complication causing significant morbidity and mortality. Drainage of the haematoma by craniotomy is associated with poor outcome. We present a patient who received tissue plasminogen activator (t-PA) for acute myocardial infarction; he subsequently developed an ICH with ventricular system extension. The patient was managed by insertion of an external ventricular drain. The hemorrhage was successfully evacuated by insertion of the external ventricular drain. This was unexpected as ICH are usually viscous and difficult to aspirate in the acute phase. This suggests that ICHs following thrombolytic therapy remain liquid for up to 10 h. External ventricular drains can be used in the management of patients with ICH complicating thrombolytic therapy for management of acute myocardial infarction or ischemic stroke. This reduces the need for craniotomy and associated morbidity and mortality.
KW - Acute intracerebral hemorrhage
KW - External ventricular drain
KW - Thrombolytic therapy
KW - Tissue plasminogen activator
UR - http://www.scopus.com/inward/record.url?scp=34447644210&partnerID=8YFLogxK
U2 - 10.1016/j.jocn.2006.06.008
DO - 10.1016/j.jocn.2006.06.008
M3 - Article
C2 - 17660059
AN - SCOPUS:34447644210
VL - 14
SP - 898
EP - 900
JO - Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
JF - Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
SN - 0967-5868
IS - 9
ER -