Intramuscular dendritic fibromyxolipoma: myxoid variant of spindle cell lipoma?

Rooshdiya Z. Karim, Stanley W. McCarthy, Allan A. Palmer, S. Fiona Bonar, Richard A. Scolyer*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

21 Citations (Scopus)


Dendritic fibromyxolipoma (DFML) is an uncommon, recently described, benign soft tissue lesion that shares many clinical and pathological features with myxoid variants of spindle cell lipoma (SCL). As described, DFML is distinguished from SCL by the presence of dendritic cytoplasmic processes, abundant keloidal collagen and a prominent, often plexiform vascular pattern. We describe the first known reported case of an intramuscular DFML that occurred in the right shoulder region of a 73-year-old man. The tumor displayed the typical histopathological features of DFML but also included foci of chondroid metaplasia, a previously unreported finding. This report also discusses the differential diagnosis, particularly distinguishing DFML from SCL and myxoid liposarcoma. In view of the similarities in many clinical and pathological features between SCL and DFML, we speculate that DFML probably represents an unusual variant of myxoid SCL.

Original languageEnglish
Pages (from-to)252-258
Number of pages7
JournalPathology International
Issue number4
Publication statusPublished - 1 Apr 2003
Externally publishedYes


  • Dendritic
  • Fibromyxolipoma
  • Lipoma
  • Liposarcoma
  • Soft tissue
  • Spindle cell lipoma


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