We sought to investigate the feasibility of using the Export catheter to sample blood from the coronary arteries for studies of platelet activation. A pilot comparison between the Export catheter and the established Simmons catheter - currently used to sample blood from the coronary sinus - was performed. Triplicate blood samples were obtained from the descending aorta for each catheter in 10 patients, and analyzed for platelet P-selectin expression, PAC-1 expression, and platelet-leukocyte aggregate formation by flow cytometry. We found no significant increase in levels of platelet activation above that of reference values and no significant differences between the two catheters.
|Number of pages||3|
|Journal||Journal of Invasive Cardiology|
|Publication status||Published - 2009|