TY - JOUR
T1 - Intravascular blood sampling using the export catheter does not induce artifactual platelet activation
AU - Yong, Andy S C
AU - Pennings, Gabrielle J.
AU - Chung, Tommy
AU - Brieger, David
AU - Lowe, Harry C.
AU - Kritharides, Leonard
PY - 2009
Y1 - 2009
N2 - We sought to investigate the feasibility of using the Export catheter to sample blood from the coronary arteries for studies of platelet activation. A pilot comparison between the Export catheter and the established Simmons catheter - currently used to sample blood from the coronary sinus - was performed. Triplicate blood samples were obtained from the descending aorta for each catheter in 10 patients, and analyzed for platelet P-selectin expression, PAC-1 expression, and platelet-leukocyte aggregate formation by flow cytometry. We found no significant increase in levels of platelet activation above that of reference values and no significant differences between the two catheters.
AB - We sought to investigate the feasibility of using the Export catheter to sample blood from the coronary arteries for studies of platelet activation. A pilot comparison between the Export catheter and the established Simmons catheter - currently used to sample blood from the coronary sinus - was performed. Triplicate blood samples were obtained from the descending aorta for each catheter in 10 patients, and analyzed for platelet P-selectin expression, PAC-1 expression, and platelet-leukocyte aggregate formation by flow cytometry. We found no significant increase in levels of platelet activation above that of reference values and no significant differences between the two catheters.
UR - http://www.scopus.com/inward/record.url?scp=67649615970&partnerID=8YFLogxK
M3 - Article
C2 - 19342753
AN - SCOPUS:67649615970
SN - 1042-3931
VL - 21
SP - 159
EP - 161
JO - Journal of Invasive Cardiology
JF - Journal of Invasive Cardiology
IS - 4
ER -