Introducing molecular selectivity in rapid impedimetric sensing of phthalates

Asif I. Zia, S. C. Mukhopadhyay, I. H. Al-Bahadly, P. L. Yu, Chinthaka P. Gooneratne, Jürgen Kosel

Research output: Chapter in Book/Report/Conference proceedingConference proceeding contributionResearchpeer-review

Abstract

This research article reports a real-time and non-invasive detection technique for phthalates in liquids by Electrochemical Impedance Spectroscopy (EIS), incorporating molecular imprinting technique to introduce selectivity for the phthalate molecule in the detection system. A functional polymer with Bis (2-ethylhexyl) phthalate (DEHP) template was immobilized on the sensing surface of the inter-digital (ID) capacitive sensor with sputtered gold sensing electrodes fabricated over a native layer of silicon dioxide on a single crystal silicon substrate. Various concentrations (10 to 200 ppm) of DEHP in deionized MilliQ water were exposed to the sensor surface functionalized with molecular imprinted polymer (MIP) in order to capture the analyte molecule, hence introducing molecular selectivity to the testing system. Impedance spectra were obtained using EIS in order to determine sample conductance for evaluation of phthalate concentration in the solution. Electrochemical Spectrum Analyzer algorithm was used to deduce equivalent circuit and equivalent component parameters from the experimentally obtained impedance spectra employing Randle's cell model curve fitting technique. Experimental results confirmed that the immobilization of the functional polymer on sensing surface introduces selectivity for phthalates in the sensing system. The results were validated by testing the samples using High Performance Liquid Chromatography (HPLC-DAD).

LanguageEnglish
Title of host publication2014 IEEE International Instrumentation and Measurement Technology Conference: Instrumentation and Measurement for Sustainable Development, I2MTC 2014 - Proceedings
Place of PublicationPiscataway, NJ
PublisherInstitute of Electrical and Electronics Engineers (IEEE)
Pages838-843
Number of pages6
ISBN (Print)9781467363853
DOIs
Publication statusPublished - 2014
Externally publishedYes
Event2014 IEEE International Instrumentation and Measurement Technology Conference: Instrumentation and Measurement for Sustainable Development, I2MTC 2014 - Montevideo, Uruguay
Duration: 12 May 201415 May 2014

Other

Other2014 IEEE International Instrumentation and Measurement Technology Conference: Instrumentation and Measurement for Sustainable Development, I2MTC 2014
CountryUruguay
CityMontevideo
Period12/05/1415/05/14

Fingerprint

Functional polymers
Electrochemical impedance spectroscopy
Capacitive sensors
Spectrum analyzers
Molecules
Deionized water
High performance liquid chromatography
Curve fitting
Testing
Equivalent circuits
Gold
Silica
Single crystals
Silicon
Electrodes
Sensors
Liquids
Polymers
Substrates

Cite this

Zia, A. I., Mukhopadhyay, S. C., Al-Bahadly, I. H., Yu, P. L., Gooneratne, C. P., & Kosel, J. (2014). Introducing molecular selectivity in rapid impedimetric sensing of phthalates. In 2014 IEEE International Instrumentation and Measurement Technology Conference: Instrumentation and Measurement for Sustainable Development, I2MTC 2014 - Proceedings (pp. 838-843). [6860861] Piscataway, NJ: Institute of Electrical and Electronics Engineers (IEEE). https://doi.org/10.1109/I2MTC.2014.6860861
Zia, Asif I. ; Mukhopadhyay, S. C. ; Al-Bahadly, I. H. ; Yu, P. L. ; Gooneratne, Chinthaka P. ; Kosel, Jürgen. / Introducing molecular selectivity in rapid impedimetric sensing of phthalates. 2014 IEEE International Instrumentation and Measurement Technology Conference: Instrumentation and Measurement for Sustainable Development, I2MTC 2014 - Proceedings. Piscataway, NJ : Institute of Electrical and Electronics Engineers (IEEE), 2014. pp. 838-843
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abstract = "This research article reports a real-time and non-invasive detection technique for phthalates in liquids by Electrochemical Impedance Spectroscopy (EIS), incorporating molecular imprinting technique to introduce selectivity for the phthalate molecule in the detection system. A functional polymer with Bis (2-ethylhexyl) phthalate (DEHP) template was immobilized on the sensing surface of the inter-digital (ID) capacitive sensor with sputtered gold sensing electrodes fabricated over a native layer of silicon dioxide on a single crystal silicon substrate. Various concentrations (10 to 200 ppm) of DEHP in deionized MilliQ water were exposed to the sensor surface functionalized with molecular imprinted polymer (MIP) in order to capture the analyte molecule, hence introducing molecular selectivity to the testing system. Impedance spectra were obtained using EIS in order to determine sample conductance for evaluation of phthalate concentration in the solution. Electrochemical Spectrum Analyzer algorithm was used to deduce equivalent circuit and equivalent component parameters from the experimentally obtained impedance spectra employing Randle's cell model curve fitting technique. Experimental results confirmed that the immobilization of the functional polymer on sensing surface introduces selectivity for phthalates in the sensing system. The results were validated by testing the samples using High Performance Liquid Chromatography (HPLC-DAD).",
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Zia, AI, Mukhopadhyay, SC, Al-Bahadly, IH, Yu, PL, Gooneratne, CP & Kosel, J 2014, Introducing molecular selectivity in rapid impedimetric sensing of phthalates. in 2014 IEEE International Instrumentation and Measurement Technology Conference: Instrumentation and Measurement for Sustainable Development, I2MTC 2014 - Proceedings., 6860861, Institute of Electrical and Electronics Engineers (IEEE), Piscataway, NJ, pp. 838-843, 2014 IEEE International Instrumentation and Measurement Technology Conference: Instrumentation and Measurement for Sustainable Development, I2MTC 2014, Montevideo, Uruguay, 12/05/14. https://doi.org/10.1109/I2MTC.2014.6860861

Introducing molecular selectivity in rapid impedimetric sensing of phthalates. / Zia, Asif I.; Mukhopadhyay, S. C.; Al-Bahadly, I. H.; Yu, P. L.; Gooneratne, Chinthaka P.; Kosel, Jürgen.

2014 IEEE International Instrumentation and Measurement Technology Conference: Instrumentation and Measurement for Sustainable Development, I2MTC 2014 - Proceedings. Piscataway, NJ : Institute of Electrical and Electronics Engineers (IEEE), 2014. p. 838-843 6860861.

Research output: Chapter in Book/Report/Conference proceedingConference proceeding contributionResearchpeer-review

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AB - This research article reports a real-time and non-invasive detection technique for phthalates in liquids by Electrochemical Impedance Spectroscopy (EIS), incorporating molecular imprinting technique to introduce selectivity for the phthalate molecule in the detection system. A functional polymer with Bis (2-ethylhexyl) phthalate (DEHP) template was immobilized on the sensing surface of the inter-digital (ID) capacitive sensor with sputtered gold sensing electrodes fabricated over a native layer of silicon dioxide on a single crystal silicon substrate. Various concentrations (10 to 200 ppm) of DEHP in deionized MilliQ water were exposed to the sensor surface functionalized with molecular imprinted polymer (MIP) in order to capture the analyte molecule, hence introducing molecular selectivity to the testing system. Impedance spectra were obtained using EIS in order to determine sample conductance for evaluation of phthalate concentration in the solution. Electrochemical Spectrum Analyzer algorithm was used to deduce equivalent circuit and equivalent component parameters from the experimentally obtained impedance spectra employing Randle's cell model curve fitting technique. Experimental results confirmed that the immobilization of the functional polymer on sensing surface introduces selectivity for phthalates in the sensing system. The results were validated by testing the samples using High Performance Liquid Chromatography (HPLC-DAD).

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BT - 2014 IEEE International Instrumentation and Measurement Technology Conference: Instrumentation and Measurement for Sustainable Development, I2MTC 2014 - Proceedings

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Zia AI, Mukhopadhyay SC, Al-Bahadly IH, Yu PL, Gooneratne CP, Kosel J. Introducing molecular selectivity in rapid impedimetric sensing of phthalates. In 2014 IEEE International Instrumentation and Measurement Technology Conference: Instrumentation and Measurement for Sustainable Development, I2MTC 2014 - Proceedings. Piscataway, NJ: Institute of Electrical and Electronics Engineers (IEEE). 2014. p. 838-843. 6860861 https://doi.org/10.1109/I2MTC.2014.6860861