Introduction of an enhanced recovery protocol for radical cystectomy

Nimalan Arumainayagam*, John McGrath, Kieran P. Jefferson, David A. Gillatt

*Corresponding author for this work

Research output: Contribution to journalArticle

141 Citations (Scopus)


OBJECTIVE: To describe and assess an enhanced recovery protocol (ERP) for the peri-operative management of patients undergoing radical cystectomy (RC), which was started at our institution on 1 October 2005, as RC is associated with increased morbidity and longer inpatient stays than other major urological procedures. PATIENTS AND METHODS: An ERP was introduced in our institution that focused on reduced bowel preparation, and standardized feeding and analgesic regimens. In all, 112 consecutive patients were compared, i.e. 56 before implementing the ERP and 56 since introducing the ERP. The primary outcome measures were duration of total inpatient stay and interval from surgery to discharge, and the morbidity and mortality. Data were analysed retrospectively from cancer network and hospital records. RESULTS: The demographics of the two groups showed no significant difference in age, gender distribution, American Society of Anesthesiologists grade, or type of urinary diversion. Re-admission, mortality and morbidity rates showed no statistically significant difference between the groups. The median (interquartile range) duration of hospital stay was 17 (15-23) days in the no-ERP group, and 13 (11-17) days in the ERP group (significantly different, P < 0.001, Wilcoxon rank-sum test). The median duration of recovery after RC was 15 (13-21) days in the no-ERP group and 12 (10-15) days in the ERP group (significantly different, P = 0.001, Wilcoxon rank-sum test). CONCLUSION: The introduction of an ERP was associated with significantly reduced hospital stay, with no deleterious effect on morbidity or mortality.

Original languageEnglish
Pages (from-to)698-701
Number of pages4
JournalBJU international
Issue number6
Publication statusPublished - Mar 2008
Externally publishedYes

Fingerprint Dive into the research topics of 'Introduction of an enhanced recovery protocol for radical cystectomy'. Together they form a unique fingerprint.

Cite this