Invasive physiological indices to determine the functional significance of coronary stenosis

Firas R. AL-Obaidi, William F. Fearon, Andy S.C. Yong

Research output: Contribution to journalReview articleResearchpeer-review

Abstract

Physiological measurements are now commonly used to assess coronary lesions in the cardiac catheterisation laboratory, and this practice is evidence-based and supported by clinical guidelines. Fractional flow reserve is currently the gold standard method to determine whether coronary lesions are functionally significant, and is used to guide revascularization. There are however several other physiological measurements that have been proposed as alternatives to the fractional flow reserve. This review aims to comprehensively discuss physiological indices that can be used in the cardiac catheterisation laboratory to determine the functional significance of coronary lesions. We will focus on their advantages and disadvantages, and the current evidence supporting their use.

LanguageEnglish
Pages39-45
Number of pages7
JournalIJC Heart and Vasculature
Volume18
DOIs
Publication statusPublished - 1 Mar 2018

Fingerprint

Coronary Stenosis
Cardiac Catheterization
Evidence-Based Practice
Guidelines

Bibliographical note

Copyright the Author(s) 2018. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.

Keywords

  • Coronary flow reserve
  • Coronary physiology
  • Fractional flow reserve
  • Resting physiological indices

Cite this

@article{b91a613b4c444729985cccbe7410ed21,
title = "Invasive physiological indices to determine the functional significance of coronary stenosis",
abstract = "Physiological measurements are now commonly used to assess coronary lesions in the cardiac catheterisation laboratory, and this practice is evidence-based and supported by clinical guidelines. Fractional flow reserve is currently the gold standard method to determine whether coronary lesions are functionally significant, and is used to guide revascularization. There are however several other physiological measurements that have been proposed as alternatives to the fractional flow reserve. This review aims to comprehensively discuss physiological indices that can be used in the cardiac catheterisation laboratory to determine the functional significance of coronary lesions. We will focus on their advantages and disadvantages, and the current evidence supporting their use.",
keywords = "Coronary flow reserve, Coronary physiology, Fractional flow reserve, Resting physiological indices",
author = "AL-Obaidi, {Firas R.} and Fearon, {William F.} and Yong, {Andy S.C.}",
note = "Copyright the Author(s) 2018. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.",
year = "2018",
month = "3",
day = "1",
doi = "10.1016/j.ijcha.2018.02.003",
language = "English",
volume = "18",
pages = "39--45",
journal = "IJC Heart and Vasculature",
issn = "2352-9067",
publisher = "Elsevier",

}

Invasive physiological indices to determine the functional significance of coronary stenosis. / AL-Obaidi, Firas R.; Fearon, William F.; Yong, Andy S.C.

In: IJC Heart and Vasculature, Vol. 18, 01.03.2018, p. 39-45.

Research output: Contribution to journalReview articleResearchpeer-review

TY - JOUR

T1 - Invasive physiological indices to determine the functional significance of coronary stenosis

AU - AL-Obaidi, Firas R.

AU - Fearon, William F.

AU - Yong, Andy S.C.

N1 - Copyright the Author(s) 2018. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.

PY - 2018/3/1

Y1 - 2018/3/1

N2 - Physiological measurements are now commonly used to assess coronary lesions in the cardiac catheterisation laboratory, and this practice is evidence-based and supported by clinical guidelines. Fractional flow reserve is currently the gold standard method to determine whether coronary lesions are functionally significant, and is used to guide revascularization. There are however several other physiological measurements that have been proposed as alternatives to the fractional flow reserve. This review aims to comprehensively discuss physiological indices that can be used in the cardiac catheterisation laboratory to determine the functional significance of coronary lesions. We will focus on their advantages and disadvantages, and the current evidence supporting their use.

AB - Physiological measurements are now commonly used to assess coronary lesions in the cardiac catheterisation laboratory, and this practice is evidence-based and supported by clinical guidelines. Fractional flow reserve is currently the gold standard method to determine whether coronary lesions are functionally significant, and is used to guide revascularization. There are however several other physiological measurements that have been proposed as alternatives to the fractional flow reserve. This review aims to comprehensively discuss physiological indices that can be used in the cardiac catheterisation laboratory to determine the functional significance of coronary lesions. We will focus on their advantages and disadvantages, and the current evidence supporting their use.

KW - Coronary flow reserve

KW - Coronary physiology

KW - Fractional flow reserve

KW - Resting physiological indices

UR - http://www.scopus.com/inward/record.url?scp=85042377358&partnerID=8YFLogxK

U2 - 10.1016/j.ijcha.2018.02.003

DO - 10.1016/j.ijcha.2018.02.003

M3 - Review article

VL - 18

SP - 39

EP - 45

JO - IJC Heart and Vasculature

T2 - IJC Heart and Vasculature

JF - IJC Heart and Vasculature

SN - 2352-9067

ER -