Investigating the scope of pseudoproline assisted peptide cyclization

Nima Sayyadi, Deni Taleski, Samira Leesch, Katrina A. Jolliffe*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

The cyclization of linear peptides from six to nine amino acids in length and containing between two and four pseudoproline turn inducers derived from serine or threonine was investigated to determine the effect of peptide length, amino acid composition and spacing between the pseudoproline residues on macrocyclization yield.

Original languageEnglish
Pages (from-to)7700-7706
Number of pages7
JournalTetrahedron
Volume70
Issue number42
DOIs
Publication statusPublished - 21 Oct 2014
Externally publishedYes

Keywords

  • Cyclic peptide
  • Macrocyclization

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