Investigating trial and treatment heterogeneity in an individual patient data meta-analysis of survival data by means of the penalized maximum likelihood approach

Mathematics

• Penalized Maximum Likelihood 100%
• Survival Data 81%
• Random Effects 44%
• Chemotherapy 38%
• Hazard Function 33%
• Treatment Effects 31%
• Cancer 29%
• Randomized Trial 19%
• Marginal Likelihood 18%
• Cox Model 18%
• Penalized Likelihood 18%
• Correlation Structure 17%
• Epidemiology 16%
• Likelihood Methods 16%
• Covariance Structure 16%
• Baseline 15%
• Incidence 13%
• Clinical Trials 13%
• Estimate 13%
• Scenarios 13%
• Interaction 10%
• Simulation Study 10%
• Relationships 8%
• Demonstrate 8%
• Estimator 8%
• Model 4%

Medicine & Life Sciences

• Data Analysis 54%
• Meta-Analysis 54%
• Survival 40%
• Head and Neck Neoplasms 36%
• Drug Therapy 21%
• Proportional Hazards Models 16%
• Epidemiology 14%
• Therapeutics 11%
• Clinical Trials 11%
• Incidence 8%