Abstract
Ferrous sulfate Fe(SO₄)₂) PVA gels were investigated for a range of absorbed doses up to 20 Gy using both magnetic resonance imaging (MRI) and spectrophotometry to determine R₁ and optical density (OD) dose responses and G values. It was found that R₁- and OD-dose sensitivities increased with O₂ saturation or by the introduction of a freeze-thaw cycle during preparation of the PVA gel. The storage temperature of the Fe(SO₄)₂)PVA gel at - 18 °C increased R-dose sensitivity above that of gels stored at 5 °C. The addition of sucrose to the formulation was found to result in the largest increase in both R₁-and OD-dose sensitivities. Fe(SO₄)₂)PVA gel with and without the addition of xylenol orange was demonstrated to have a G value of Ο20 ions/100 eV and with sucrose Ο24 ions/100 eV.
Original language | English |
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Pages (from-to) | 4233-4246 |
Number of pages | 14 |
Journal | Physics in Medicine and Biology |
Volume | 47 |
Issue number | 23 |
DOIs | |
Publication status | Published - 2002 |
Externally published | Yes |