Investigation of trapping process in "Centrifuge-on-a-chip"

Jun Zhang, Ming Li, Weihua Li, Gursel Alici

Research output: Chapter in Book/Report/Conference proceedingConference proceeding contributionpeer-review

1 Citation (Scopus)

Abstract

"Centrifuge-on-a-chip" is a versatile and multifunctional microfluidic chip which can conduct operations of selective trapping, enrichment, labeling and solution exchange. In this work, the mechanism of selective trapping ability was studied by both the experiments and numerical simulation. We proved the existence of shear gradient lift force in the expansion-contraction cavity and derived an explicit expression of it. Also, a numerical modeling was developed to study the trapping process of micro-particles in a "Centrifuge-on-a-chip". The effects of flow condition and particle size on the trapping process were investigated. It demonstrates that the derived expression and developed model are suitable for the prediction of particles' trapping process, which can assist the design of "Centrifuge-on-a-chip".
Original languageEnglish
Title of host publication2013 IEEE/ASME International Conference on Advanced Intelligent Mechatronics
Subtitle of host publicationMechatronics for Human Wellbeing
Place of PublicationPiscataway, NJ
PublisherInstitute of Electrical and Electronics Engineers (IEEE)
Pages1266-1271
Number of pages6
ISBN (Electronic)9781467353205, 9781467353182
ISBN (Print)9781467353199
DOIs
Publication statusPublished - 2013
Externally publishedYes

Publication series

Name
ISSN (Print)2159-6247
ISSN (Electronic)2159-6255

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