Abstract
Our research reports an innovative label-free detection methodology for measuring creatinine in kidney healthcare management at an early stage. A Micro Electro-Mechanical-Systems (MEMS)-based interdigital (ID) sensor combined with Electrochemical Impedance Spectroscopy (EIS) technique is used in studying the reactance and capacitance properties of the serum creatinine samples. Molecularly Imprinted Polymer (MIP) having highly specific detection sites for creatinine are developed. The MEMS ID sensor's sensing area is coated with the developed MIP for selectively increasing the sensitivity and specificity of the MEMS ID sensor to creatinine. A known serum creatinine samples are tested using a developed Internet of Things (IoT) enabled Point-of-Care (PoC) diagnostic device prototype system. The developed PoC device results are cross-verified using standard Creatinine Colorimetric Assay Kit. The PoC device's obtained results are user friendly, inspiring, inexpensive, faster and precise for the early detection of creatinine rise for kidney healthcare.
Original language | English |
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Title of host publication | Sensing technology |
Subtitle of host publication | proceedings of ICST 2022 |
Editors | Nagender Kumar Suryadevara, Boby George, Krishanthi P. Jayasundera, Joyanta Kumar Roy, Subhas Chandra Mukhopadhyay |
Place of Publication | Cham, Switzerland |
Publisher | Springer, Springer Nature |
Pages | 257–268 |
Number of pages | 12 |
ISBN (Electronic) | 9783030988869 |
ISBN (Print) | 9783030988852 |
DOIs | |
Publication status | Published - 2022 |
Event | International Conference on Sensing Technology (14th : ICST 2022) - Indian Institute of Technology Madras, Chennai, India Duration: 16 Jan 2022 → 18 Jan 2022 Conference number: 14th |
Publication series
Name | Lecture Notes in Electrical Engineering |
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Publisher | Springer |
Volume | 886 |
ISSN (Print) | 1876-1100 |
ISSN (Electronic) | 1876-1119 |
Conference
Conference | International Conference on Sensing Technology (14th : ICST 2022) |
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Abbreviated title | ICST 2022 |
Country/Territory | India |
City | Chennai |
Period | 16/01/22 → 18/01/22 |
Keywords
- Micro-Electro-Mechanical-Systems (MEMS)
- Electrochemical Impedance Spectroscopy (EIS)
- Molecularly Imprinted Polymer (MIP)
- Point-of-Care (PoC)