"Iron mining" to inhibit tumor growth

Des R. Richardson*, David B. Lovejoy

*Corresponding author for this work

Research output: Contribution to journalComment/opinion

Abstract

Control of tumor growth by new strategies remains a vital research goal. Nie and
associates convincingly demonstrate that expression of mitochondrial ferritin leads
to mitochondrial iron sequestration, which inhibits tumor growth in vivo. This
work illustrates the potential importance of the mitochondrion in controlling iron
metabolism and confirms that iron deprivation is an effective method to prevent
cancer growth.
Original languageEnglish
Pages (from-to)2140
Number of pages1
JournalBlood
Volume108
Issue number7
DOIs
Publication statusPublished - 1 Oct 2006
Externally publishedYes

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