Isolated symptomatic cutaneous disease in hypereosinophilic syndrome

Veronica Preda, Christopher Henderson, Jane Woods

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


A 41-year-old Phillipino man presented with a 3-year history of a relapsing and remitting generalized chronic pruritic erythematous papular and plaque-like eruption. Investigations showed a persistently elevated eosinophil count. His disease was limited to cutaneous involvement with an absence of demonstrable internal organ involvement, despite extensive investigations and multidisciplinary review. Other causes of eosinophilia were excluded. A diagnosis of idiopathic hypereosinophilic syndrome was made. Our patient's presentation raises a number of issues related to hypereosinophilic syndrome. In particular, relating to managing hypereosinophilic syndrome and the challenge of minimizing therapy side-effects. Our case highlights the considerable morbidity of untreated isolated cutaneous disease, for which he was hospitalized with suicidal ideations. In a minority of reports, skin involvement is the only manifestation of hypereosinophilic syndrome.

Original languageEnglish
Pages (from-to)60-65
Number of pages6
JournalAustralasian Journal of Dermatology
Issue number1
Publication statusPublished - Feb 2010
Externally publishedYes


  • Adult
  • Diagnosis, Differential
  • Humans
  • Hypereosinophilic Syndrome
  • Male
  • Pruritus
  • Suicide
  • Case Reports
  • Journal Article


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