Large-area gold nanohole arrays fabricated by one-step method for surface plasmon resonance biochemical sensing

Huijie Qi, Lihong Niu, Jie Zhang, Jian Chen, Shujie Wang, Jingjing Yang, Siyi Guo, Tom Lawson, Bingyang Shi*, Chunpeng Song

*Corresponding author for this work

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Surface plasmon resonance (SPR) nanosensors based on metallic nanohole arrays have been widely reported to detect binding interactions in biological specimens. A simple and effective method for constructing nanoscale arrays is essential for the development of SPR nanosensors. In this work, we report a one-step method to fabricate nanohole arrays by thermal nanoimprinting in the matrix of IPS (Intermediate Polymer Stamp). No additional etching process or supporting substrate is required. The preparation process is simple, time-saving and compatible for roll-to-roll process, potentially allowing mass production. Moreover, the nanohole arrays were integrated into detection platform as SPR sensors to investigate different types of biological binding interactions. The results demonstrate that our one-step method can be used to efficiently fabricate large-area and uniform nanohole arrays for biochemical sensing.

Original languageEnglish
Pages (from-to)476-482
Number of pages7
JournalScience China Life Sciences
Volume61
Issue number4
DOIs
Publication statusPublished - 1 Apr 2018

Keywords

  • biomolecular binding
  • gold nanohole arrays
  • nanoimprinting
  • nanosensor
  • one-step method

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