Laser vascular welding-How does it work?

Rodney A. White*, George Kopchok, Shi Kaung Peng, Roy Fujitani, Geoffrey White, Stanley Klein, Jouni Uitto

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    30 Citations (Scopus)


    This study evaluated the histology and electron microscopy of four samples of 2 cm long venotomles and artery-vein anastomoses formed in canine femoral arteries and veins using the argon laser (0.5 W power, 1 800 J/cm2, 4 min exposure/1 cm length of anastomosis). Welds were continuously irrigated with saline during the procedure to limit maximal temperatures to 44.2±1.6°C (mean±SD), and the specimens were removed immediately following fusion and preserved for examination. Histologic and electron microscopic examination of different areas of the welds revealed various mechanisms of fusion including a) apposition of denatured collagen and elastin in the media and adventitia; b) bonding of veln medial collagen and elastin to the internal elastic membrane of the artery; and c) fusion consisting of a coagulum of platelets and fibrin depending on the allgnment and apposition of the vessel edges. This study demonstrates that vascular tissue fusion by the argon laser occurs by various mechanisms. Future experiments should delineate which types of seal produce the optimal strength at the time of fusion, and enhance longterm healing.

    Original languageEnglish
    Pages (from-to)461-464
    Number of pages4
    JournalAnnals of vascular surgery
    Issue number4
    Publication statusPublished - May 1987


    • Laser
    • Vascular anastomosis


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