Lead from calcium supplements contributes minimally to blood lead concentrations

Brian Gulson*, Karen Mizon, Jacqueline Palmer, Michael Korsch, Alan Taylor

*Corresponding author for this work

Research output: Contribution to journalMeeting abstract


We undertook a study using lead isotopes to determine the contribution of lead to blood from consumption of calcium supplements approximating the recommended daily intakes over a 6 month period. Subjects were subdivided into three groups. One treatment group (n=8) was administered a complex calcium supplement (carbonate/phosphate/citrate) and the other treatment group (n=7), calcium carbonate. The control group (n=6) received no supplementation. The lead isotopic compositions of the supplements were completely different from those of the blood of the subjects. Lead isotopic compositions for the complex supplement showed minimal change during treatment compared with pre-treatment. Lead isotopic compositions in blood for the calcium carbonate supplements showed increases of up to 0.5% in the 206Pb/204Pb ratio, and for all isotope ratios there was a statistically significant difference between baseline and treatment (p<0.005). Blood lead concentrations showed minimal changes.

Original languageEnglish
Pages (from-to)597-600
Number of pages4
JournalJournal De Physique. IV : JP
Issue numberI
Publication statusPublished - May 2003
EventXIIth International Conference on Heavy Metals in the Environment - Grenoble France
Duration: 26 May 200330 May 2003

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