Lead from calcium supplements contributes minimally to blood lead concentrations

Brian Gulson; Karen Mizon; Jacqueline Palmer; Michael Korsch; Alan Taylor

doi:10.1051/jp4:20030374

Abstract

We undertook a study using lead isotopes to determine the contribution of lead to blood from consumption of calcium supplements approximating the recommended daily intakes over a 6 month period. Subjects were subdivided into three groups. One treatment group (n=8) was administered a complex calcium supplement (carbonate/phosphate/citrate) and the other treatment group (n=7), calcium carbonate. The control group (n=6) received no supplementation. The lead isotopic compositions of the supplements were completely different from those of the blood of the subjects. Lead isotopic compositions for the complex supplement showed minimal change during treatment compared with pre-treatment. Lead isotopic compositions in blood for the calcium carbonate supplements showed increases of up to 0.5% in the ²⁰⁶Pb/²⁰⁴Pb ratio, and for all isotope ratios there was a statistically significant difference between baseline and treatment (p<0.005). Blood lead concentrations showed minimal changes.

Original language	English
Pages (from-to)	597-600
Number of pages	4
Journal	Journal De Physique. IV : JP
Volume	107
Issue number	I
DOIs	https://doi.org/10.1051/jp4:20030374
Publication status	Published - May 2003
Event	XIIth International Conference on Heavy Metals in the Environment - Grenoble France Duration: 26 May 2003 → 30 May 2003

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title = "Lead from calcium supplements contributes minimally to blood lead concentrations",

abstract = "We undertook a study using lead isotopes to determine the contribution of lead to blood from consumption of calcium supplements approximating the recommended daily intakes over a 6 month period. Subjects were subdivided into three groups. One treatment group (n=8) was administered a complex calcium supplement (carbonate/phosphate/citrate) and the other treatment group (n=7), calcium carbonate. The control group (n=6) received no supplementation. The lead isotopic compositions of the supplements were completely different from those of the blood of the subjects. Lead isotopic compositions for the complex supplement showed minimal change during treatment compared with pre-treatment. Lead isotopic compositions in blood for the calcium carbonate supplements showed increases of up to 0.5% in the 206Pb/204Pb ratio, and for all isotope ratios there was a statistically significant difference between baseline and treatment (p<0.005). Blood lead concentrations showed minimal changes.",

author = "Brian Gulson and Karen Mizon and Jacqueline Palmer and Michael Korsch and Alan Taylor",

year = "2003",

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journal = "Journal De Physique. IV : JP",

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TY - JOUR

T1 - Lead from calcium supplements contributes minimally to blood lead concentrations

AU - Gulson, Brian

AU - Mizon, Karen

AU - Palmer, Jacqueline

AU - Korsch, Michael

AU - Taylor, Alan

PY - 2003/5

Y1 - 2003/5

N2 - We undertook a study using lead isotopes to determine the contribution of lead to blood from consumption of calcium supplements approximating the recommended daily intakes over a 6 month period. Subjects were subdivided into three groups. One treatment group (n=8) was administered a complex calcium supplement (carbonate/phosphate/citrate) and the other treatment group (n=7), calcium carbonate. The control group (n=6) received no supplementation. The lead isotopic compositions of the supplements were completely different from those of the blood of the subjects. Lead isotopic compositions for the complex supplement showed minimal change during treatment compared with pre-treatment. Lead isotopic compositions in blood for the calcium carbonate supplements showed increases of up to 0.5% in the 206Pb/204Pb ratio, and for all isotope ratios there was a statistically significant difference between baseline and treatment (p<0.005). Blood lead concentrations showed minimal changes.

AB - We undertook a study using lead isotopes to determine the contribution of lead to blood from consumption of calcium supplements approximating the recommended daily intakes over a 6 month period. Subjects were subdivided into three groups. One treatment group (n=8) was administered a complex calcium supplement (carbonate/phosphate/citrate) and the other treatment group (n=7), calcium carbonate. The control group (n=6) received no supplementation. The lead isotopic compositions of the supplements were completely different from those of the blood of the subjects. Lead isotopic compositions for the complex supplement showed minimal change during treatment compared with pre-treatment. Lead isotopic compositions in blood for the calcium carbonate supplements showed increases of up to 0.5% in the 206Pb/204Pb ratio, and for all isotope ratios there was a statistically significant difference between baseline and treatment (p<0.005). Blood lead concentrations showed minimal changes.

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DO - 10.1051/jp4:20030374

M3 - Meeting abstract

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SN - 1155-4339

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JO - Journal De Physique. IV : JP

JF - Journal De Physique. IV : JP

IS - I

T2 - XIIth International Conference on Heavy Metals in the Environment

Y2 - 26 May 2003 through 30 May 2003

ER -

Lead from calcium supplements contributes minimally to blood lead concentrations

Abstract

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