We undertook a study using lead isotopes to determine the contribution of lead to blood from consumption of calcium supplements approximating the recommended daily intakes over a 6 month period. Subjects were subdivided into three groups. One treatment group (n=8) was administered a complex calcium supplement (carbonate/phosphate/citrate) and the other treatment group (n=7), calcium carbonate. The control group (n=6) received no supplementation. The lead isotopic compositions of the supplements were completely different from those of the blood of the subjects. Lead isotopic compositions for the complex supplement showed minimal change during treatment compared with pre-treatment. Lead isotopic compositions in blood for the calcium carbonate supplements showed increases of up to 0.5% in the 206Pb/204Pb ratio, and for all isotope ratios there was a statistically significant difference between baseline and treatment (p<0.005). Blood lead concentrations showed minimal changes.
|Number of pages||4|
|Journal||Journal De Physique. IV : JP|
|Publication status||Published - May 2003|
|Event||XIIth International Conference on Heavy Metals in the Environment - Grenoble France|
Duration: 26 May 2003 → 30 May 2003