Life at depth: Photobacterium profundum genome sequence and expression analysis

A. Vezzi; S. Campanaro; M. D'Angelo; F. Simonato; N. Vitulo; F. M. Lauro; A. Cestaro; G. Malacrida; B. Simionati; N. Cannata; C. Romualdi; D. H. Bartlett; G. Valle

doi:10.1126/science.1103341

Life at depth: Photobacterium profundum genome sequence and expression analysis

A. Vezzi, S. Campanaro, M. D'Angelo, F. Simonato, N. Vitulo, F. M. Lauro, A. Cestaro, G. Malacrida, B. Simionati, N. Cannata, C. Romualdi, D. H. Bartlett, G. Valle^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

223 Citations (Scopus)

Abstract

Deep-sea life requires adaptation to high pressure, an extreme yet common condition given that oceans cover 70% of Earth's surface and have an average depth of 3800 meters. Survival at such depths requires specific adaptation but, compared with other extreme conditions, high pressure has received little attention. Recently, Photobacterium profundum strain SS9 has been adopted as a model for piezophily. Here we report its genome sequence (6.4 megabase pairs) and transcriptome analysis. The results provide a first glimpse into the molecular basis for life in the largest portion of the biosphere, revealing high metabolic versatility.

Original language	English
Pages (from-to)	1459-1461
Number of pages	3
Journal	Science
Volume	307
Issue number	5714
DOIs	https://doi.org/10.1126/science.1103341
Publication status	Published - 4 Mar 2005
Externally published	Yes

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title = "Life at depth: Photobacterium profundum genome sequence and expression analysis",

abstract = "Deep-sea life requires adaptation to high pressure, an extreme yet common condition given that oceans cover 70% of Earth's surface and have an average depth of 3800 meters. Survival at such depths requires specific adaptation but, compared with other extreme conditions, high pressure has received little attention. Recently, Photobacterium profundum strain SS9 has been adopted as a model for piezophily. Here we report its genome sequence (6.4 megabase pairs) and transcriptome analysis. The results provide a first glimpse into the molecular basis for life in the largest portion of the biosphere, revealing high metabolic versatility.",

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T2 - Photobacterium profundum genome sequence and expression analysis

AU - Vezzi, A.

AU - Campanaro, S.

AU - D'Angelo, M.

AU - Simonato, F.

AU - Vitulo, N.

AU - Lauro, F. M.

AU - Cestaro, A.

AU - Malacrida, G.

AU - Simionati, B.

AU - Cannata, N.

AU - Romualdi, C.

AU - Bartlett, D. H.

AU - Valle, G.

PY - 2005/3/4

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N2 - Deep-sea life requires adaptation to high pressure, an extreme yet common condition given that oceans cover 70% of Earth's surface and have an average depth of 3800 meters. Survival at such depths requires specific adaptation but, compared with other extreme conditions, high pressure has received little attention. Recently, Photobacterium profundum strain SS9 has been adopted as a model for piezophily. Here we report its genome sequence (6.4 megabase pairs) and transcriptome analysis. The results provide a first glimpse into the molecular basis for life in the largest portion of the biosphere, revealing high metabolic versatility.

AB - Deep-sea life requires adaptation to high pressure, an extreme yet common condition given that oceans cover 70% of Earth's surface and have an average depth of 3800 meters. Survival at such depths requires specific adaptation but, compared with other extreme conditions, high pressure has received little attention. Recently, Photobacterium profundum strain SS9 has been adopted as a model for piezophily. Here we report its genome sequence (6.4 megabase pairs) and transcriptome analysis. The results provide a first glimpse into the molecular basis for life in the largest portion of the biosphere, revealing high metabolic versatility.

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Life at depth: Photobacterium profundum genome sequence and expression analysis

Abstract

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