Light-induced liposomes for cancer therapeutics

Wenjie Chen, Ewa M. Goldys, Wei Deng*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

5 Citations (Scopus)

Abstract

The emerging nanomedicine therapeutics have incorporated photonics technologies to develop precise medical treatment. Among the light regulated approaches, light-induced liposome technology has been explored and developed as a novel tool for spatiotemporal control of cargo release. Compared with the traditional liposome formulation, this triggering feature largely enhanced the therapeutic efficacy and minimized the side effects of the therapeutic substance. In this review paper, we discussed the basics of the light-induced liposomes including the engineering methods and photoresponsiveness mechanisms. We also reviewed current biomedical studies relating to light-induced liposome delivery systems, with an emphasis in the field of cancer therapy.

Original languageEnglish
Article number101052
Pages (from-to)1-16
Number of pages16
JournalProgress in Lipid Research
Volume79
DOIs
Publication statusPublished - Jul 2020
Externally publishedYes

Keywords

  • Cancer therapeutics
  • Drug/gene delivery
  • Light triggering
  • Liposomes

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