Limited clinical utility of high-sensitivity plasma C-reactive protein assays

Bruce Campbell; Tony Badrick; Robert Flatman; David Kanowski

doi:10.1258/0004563021901757

Limited clinical utility of high-sensitivity plasma C-reactive protein assays

Bruce Campbell^*, Tony Badrick, Robert Flatman, David Kanowski

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

49 Citations (Scopus)

Abstract

Many recent studies have shown a relationship between plasma C-reactive protein (CRP) concentrations and risk of cardiovascular disease. However, the intraindividual variation in plasma CRP concentrations is large. Use of plasma CRP measurement in individual patients is like]y to result in many being misclassified in their risk status. Use of repeated measurements is not a practical solution to this problem.

Original language	English
Pages (from-to)	85-88
Number of pages	4
Journal	Annals of Clinical Biochemistry
Volume	39
Issue number	2
DOIs	https://doi.org/10.1258/0004563021901757
Publication status	Published - 2002
Externally published	Yes

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title = "Limited clinical utility of high-sensitivity plasma C-reactive protein assays",

abstract = "Many recent studies have shown a relationship between plasma C-reactive protein (CRP) concentrations and risk of cardiovascular disease. However, the intraindividual variation in plasma CRP concentrations is large. Use of plasma CRP measurement in individual patients is like]y to result in many being misclassified in their risk status. Use of repeated measurements is not a practical solution to this problem.",

author = "Bruce Campbell and Tony Badrick and Robert Flatman and David Kanowski",

year = "2002",

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language = "English",

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AU - Campbell, Bruce

AU - Badrick, Tony

AU - Flatman, Robert

AU - Kanowski, David

PY - 2002

Y1 - 2002

N2 - Many recent studies have shown a relationship between plasma C-reactive protein (CRP) concentrations and risk of cardiovascular disease. However, the intraindividual variation in plasma CRP concentrations is large. Use of plasma CRP measurement in individual patients is like]y to result in many being misclassified in their risk status. Use of repeated measurements is not a practical solution to this problem.

AB - Many recent studies have shown a relationship between plasma C-reactive protein (CRP) concentrations and risk of cardiovascular disease. However, the intraindividual variation in plasma CRP concentrations is large. Use of plasma CRP measurement in individual patients is like]y to result in many being misclassified in their risk status. Use of repeated measurements is not a practical solution to this problem.

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U2 - 10.1258/0004563021901757

DO - 10.1258/0004563021901757

M3 - Review article

C2 - 11928769

AN - SCOPUS:0036191680

SN - 0004-5632

VL - 39

SP - 85

EP - 88

JO - Annals of Clinical Biochemistry

JF - Annals of Clinical Biochemistry

IS - 2

ER -

Limited clinical utility of high-sensitivity plasma C-reactive protein assays

Abstract

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