Linear dichroism for the detection of single base pair mutations

D. J. Halsall, A. Rodger*, T. R. Dafforn

*Corresponding author for this work

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Flow linear dichroism is shown to be able to detect single base mismatches in a polymerase chain reaction (PCR) amplimers from exon 10 of the human β-glucocerebrosidase gene (associated with Gaucher disease) over a kilobase long with no post PCR manipulation.

Original languageEnglish
Pages (from-to)2410-2411
Number of pages2
JournalChemical Communications
Issue number23
Publication statusPublished - 7 Dec 2001
Externally publishedYes

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