Abstract
This work developed a facile and environmentally friendly route for lipase-catalyzed synthesis of a hyperbranched polyester by introducing an autocatalytic prepolymerization of comonomers. Trimethylolpropane, 1,8-octanediol, and adipic acid as comonomers for synthesizing the hyperbranched polyester were first prepolymerized via the automatic catalytic effect of the reactants themselves to obtain an appropriate reaction substrate for further lipase-catalyzed polymerization, where immobilized lipase Novozym 435 was used as a biocatalyst. The acidity and fluidity of optimized oligomers after the autocatalytic prepolymerization provide a benign reaction substrate for the retention of enzymatic activity in the subsequent lipase-catalyzed esterification, which is crucial for the enzymatic polymerization. The optimum reaction temperature and reaction time for prepolymerization were determined to be 120 °C and 150 min. The molecular weight (Mw) of the prepared polyester was approximately 26,300 g/mol. Quantitative analysis of 1H-NMR and inverse-gated 13C-NMR spectra confirmed the hyperbranched structure of the resulting polyester with a branching degree of 31.3%.
| Language | English |
|---|---|
| Article number | 47221 |
| Pages | 1-8 |
| Number of pages | 8 |
| Journal | Journal of Applied Polymer Science |
| Volume | 136 |
| Issue number | 12 |
| Early online date | 30 Oct 2018 |
| DOIs | |
| Publication status | Published - 20 Mar 2019 |
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Keywords
- condensation polymerization
- dendrimers
- hyperbranched polymers and macrocycles
- polyesters
- synthesis and processing techniques
- ALIPHATIC POLYESTERS
- ORGANIC-SOLVENTS
- VESICLES
- POLY-L-LACTIDE
- WATER
Cite this
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Lipase-catalyzed synthesis of hyperbranched polyester improved by autocatalytic prepolymerization process. / Liang, Liuen; Long, Junyuan; Li, Guangji.
In: Journal of Applied Polymer Science, Vol. 136, No. 12, 47221, 20.03.2019, p. 1-8.Research output: Contribution to journal › Article › Research › peer-review
TY - JOUR
T1 - Lipase-catalyzed synthesis of hyperbranched polyester improved by autocatalytic prepolymerization process
AU - Liang, Liuen
AU - Long, Junyuan
AU - Li, Guangji
PY - 2019/3/20
Y1 - 2019/3/20
N2 - This work developed a facile and environmentally friendly route for lipase-catalyzed synthesis of a hyperbranched polyester by introducing an autocatalytic prepolymerization of comonomers. Trimethylolpropane, 1,8-octanediol, and adipic acid as comonomers for synthesizing the hyperbranched polyester were first prepolymerized via the automatic catalytic effect of the reactants themselves to obtain an appropriate reaction substrate for further lipase-catalyzed polymerization, where immobilized lipase Novozym 435 was used as a biocatalyst. The acidity and fluidity of optimized oligomers after the autocatalytic prepolymerization provide a benign reaction substrate for the retention of enzymatic activity in the subsequent lipase-catalyzed esterification, which is crucial for the enzymatic polymerization. The optimum reaction temperature and reaction time for prepolymerization were determined to be 120 °C and 150 min. The molecular weight (Mw) of the prepared polyester was approximately 26,300 g/mol. Quantitative analysis of 1H-NMR and inverse-gated 13C-NMR spectra confirmed the hyperbranched structure of the resulting polyester with a branching degree of 31.3%.
AB - This work developed a facile and environmentally friendly route for lipase-catalyzed synthesis of a hyperbranched polyester by introducing an autocatalytic prepolymerization of comonomers. Trimethylolpropane, 1,8-octanediol, and adipic acid as comonomers for synthesizing the hyperbranched polyester were first prepolymerized via the automatic catalytic effect of the reactants themselves to obtain an appropriate reaction substrate for further lipase-catalyzed polymerization, where immobilized lipase Novozym 435 was used as a biocatalyst. The acidity and fluidity of optimized oligomers after the autocatalytic prepolymerization provide a benign reaction substrate for the retention of enzymatic activity in the subsequent lipase-catalyzed esterification, which is crucial for the enzymatic polymerization. The optimum reaction temperature and reaction time for prepolymerization were determined to be 120 °C and 150 min. The molecular weight (Mw) of the prepared polyester was approximately 26,300 g/mol. Quantitative analysis of 1H-NMR and inverse-gated 13C-NMR spectra confirmed the hyperbranched structure of the resulting polyester with a branching degree of 31.3%.
KW - condensation polymerization
KW - dendrimers
KW - hyperbranched polymers and macrocycles
KW - polyesters
KW - synthesis and processing techniques
KW - ALIPHATIC POLYESTERS
KW - ORGANIC-SOLVENTS
KW - VESICLES
KW - POLY-L-LACTIDE
KW - WATER
UR - http://www.scopus.com/inward/record.url?scp=85055740590&partnerID=8YFLogxK
U2 - 10.1002/app.47221
DO - 10.1002/app.47221
M3 - Article
VL - 136
SP - 1
EP - 8
JO - Journal of Applied Polymer Science
T2 - Journal of Applied Polymer Science
JF - Journal of Applied Polymer Science
SN - 0021-8995
IS - 12
M1 - 47221
ER -