Long-term auditory processing outcomes in early implanted young adults with cochlear implants: the mismatch negativity vs. P300 response

Rosanne Abrahamse*, Andy Beynon, Vitoria Piai

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Objective
Long-term outcomes of early implanted, young adult cochlear implant (CI) users remain variable. We measured auditory discrimination by means of event-related potentials in this population to examine whether variability at the level of cortical auditory processing helps to explain speech abilities.
Methods
Using an auditory oddball paradigm, the P300 and Mismatch Negativity (MMN) were measured in 8 young adult CI users and 14 normal-hearing peers. We related P300 amplitude and latency to clinical speech perception scores in quiet and to duration of deafness.
Results
All individuals showed P300 responses. The MMN response was less robust in both groups. There was no evidence for differences in P300 responses between CI users and controls. P300 amplitude was associated with speech perception scores (r = 0.70, p = .05) and duration of deafness (r = −0.83, p = .009).
Conclusions
Early CI implantation yields good auditory processing outcomes at young adult age and, in contrast to MMN, the P300 provides a robust measure for auditory processing on an individual level.
Significance
At the cortical level, early implanted, long-term CI users have good auditory discrimination, leaving variability in implantation outcomes unexplained. This group provides unique insight into the long-term neurophysiological underpinnings of early implantation.
Original languageEnglish
Pages (from-to)258-268
Number of pages11
JournalClinical Neurophysiology
Volume132
Issue number1
Early online date16 Oct 2020
DOIs
Publication statusPublished - Jan 2021
Externally publishedYes

Keywords

  • cochlear implants
  • auditory cortical response
  • auditory discrimination
  • P300
  • Mismatch Negativity (MMN)
  • speech perception

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