Long term outcomes following Freestyle stentless aortic bioprosthesis implantation: an Australian experience

Andrew G. Sherrah, Richmond W. Jeremy, Rajesh Puranik, Paul G. Bannon, P. Nicholas Hendel, Matthew S. Bayfield, Michael K. Wilson, Peter W. Brady, David Marshman, Manu N. Mathur, R. John Brereton, James R. Edwards, Robert G. Stuklis, Michael Worthington, Michael P. Vallely*

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    5 Citations (Scopus)

    Abstract

    Background: The Freestyle stentless bioprosthesis (FSB) has been demonstrated to be a durable prosthesis in the aortic position. We present data following Freestyle implantation for up to 10 years post-operatively and compare this with previously published results.

    Methods: A retrospective cohort analysis of 237 patients following FSB implantation occurred at five Australian hospitals. Follow-up data included clinical and echocardiographic outcomes.

    Results: The cohort was 81.4% male with age 63.2±13.0 years and was followed for a mean of 2.4±2.3 years (range 0-10.9 years, total 569 patient-years). The FSB was implanted as a full aortic root replacement in 87.8% patients. The 30-day all cause mortality was 4.2% (2.0% for elective surgery). Cumulative survival at one, five and 10 years was 91.7±1.9%, 82.8±3.8% and 56.5±10.5%, respectively. Freedom from re-intervention at one, five and 10 years was 99.5±0.5%, 91.6±3.7% and 72.3±10.5%, respectively. At latest echocardiographic review (mean 2.3±2.1 years post-operatively), 92.6% had trivial or no aortic regurgitation. Predictors of post-operative mortality included active endocarditis, acute aortic dissection and peripheral vascular disease.

    Conclusions: We report acceptable short and long term outcomes following FSB implantation in a cohort of comparatively younger patients with thoracic aortic disease. The durability of this bioprosthesis in the younger population remains to be confirmed.

    Original languageEnglish
    Pages (from-to)82-88
    Number of pages7
    JournalHeart, Lung and Circulation
    Volume25
    Issue number1
    DOIs
    Publication statusPublished - Jan 2016

    Keywords

    • aortic valve
    • heart valve prosthesis
    • bioprosthesis
    • aorta
    • thoracic
    • aortic aneurysm

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