Low-grade myxoid chondrosarcoma of the temporal bone

differential diagnosis and report of two cases

Colin B. A. Reid, Paul A. Fagan*, Jennifer Turner

*Corresponding author for this work

Research output: Contribution to journalArticle

11 Citations (Scopus)


Skull base chondrosarcoma and chordoma are rare tumors that generally have a poor prognosis. In 1973, Heffelfinger et al described a chondroid variant of chordoma, called chondroid chordoma that was found to have a significantly better prognosis than classic chordoma. However, recent evidence suggests that many of the tumors diagnosed as chondroid chordoma may, in fact, be low- grade myxoid chondrosarcomas. This report presents the diagnosis and treatment of two cases of skull base tumor that were diagnosed preoperatively as schwannoma because they were thought initially to be centred on the jugular foramen. Initial histologic evaluation suggested chondroid chordoma, but immunohistologic techniques and a review of the literature led to a diagnosis of low-grade myxoid chondrosarcoma.

Original languageEnglish
Pages (from-to)419-422
Number of pages4
JournalAmerican Journal of Otology
Issue number3
Publication statusPublished - 1994

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