Luminescence studies of the intracellular distribution of a dinuclear gold(I) N-heterocyclic carbene complex

Peter J. Barnard; Louise E. Wedlock; Murray V. Baker; Susan J. Berners-Price; David A. Joyce; Brian W. Skelton; James H. Steer

doi:10.1002/anie.200601526

Luminescence studies of the intracellular distribution of a dinuclear gold(I) N-heterocyclic carbene complex

Peter J. Barnard^*, Louise E. Wedlock, Murray V. Baker, Susan J. Berners-Price, David A. Joyce, Brian W. Skelton, James H. Steer

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

229 Citations (Scopus)

Abstract

(Figure Presented) Gold lights the way: A bidentate cyclophane N-heterocyclic carbene ligand has been used to synthesize a new dinuclear Au^I complex of the formula [Au₂L₂] ²⁺. The short Au⋯Au distance imposed by the rigid cyclophane ligand leads to a red-shifted luminescence profile that enables the complex to be used as a luminescent probe for distribution studies in single living cancer cells.

Original language	English
Pages (from-to)	5966-5970
Number of pages	5
Journal	Angewandte Chemie - International Edition
Volume	45
Issue number	36
DOIs	https://doi.org/10.1002/anie.200601526
Publication status	Published - 11 Sept 2006
Externally published	Yes

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title = "Luminescence studies of the intracellular distribution of a dinuclear gold(I) N-heterocyclic carbene complex",

abstract = "(Figure Presented) Gold lights the way: A bidentate cyclophane N-heterocyclic carbene ligand has been used to synthesize a new dinuclear AuI complex of the formula [Au2L2] 2+. The short Au⋯Au distance imposed by the rigid cyclophane ligand leads to a red-shifted luminescence profile that enables the complex to be used as a luminescent probe for distribution studies in single living cancer cells.",

author = "Barnard, {Peter J.} and Wedlock, {Louise E.} and Baker, {Murray V.} and Berners-Price, {Susan J.} and Joyce, {David A.} and Skelton, {Brian W.} and Steer, {James H.}",

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AU - Barnard, Peter J.

AU - Wedlock, Louise E.

AU - Baker, Murray V.

AU - Berners-Price, Susan J.

AU - Joyce, David A.

AU - Skelton, Brian W.

AU - Steer, James H.

PY - 2006/9/11

Y1 - 2006/9/11

N2 - (Figure Presented) Gold lights the way: A bidentate cyclophane N-heterocyclic carbene ligand has been used to synthesize a new dinuclear AuI complex of the formula [Au2L2] 2+. The short Au⋯Au distance imposed by the rigid cyclophane ligand leads to a red-shifted luminescence profile that enables the complex to be used as a luminescent probe for distribution studies in single living cancer cells.

AB - (Figure Presented) Gold lights the way: A bidentate cyclophane N-heterocyclic carbene ligand has been used to synthesize a new dinuclear AuI complex of the formula [Au2L2] 2+. The short Au⋯Au distance imposed by the rigid cyclophane ligand leads to a red-shifted luminescence profile that enables the complex to be used as a luminescent probe for distribution studies in single living cancer cells.

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U2 - 10.1002/anie.200601526

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AN - SCOPUS:33748767913

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JO - Angewandte Chemie - International Edition

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IS - 36

ER -

Luminescence studies of the intracellular distribution of a dinuclear gold(I) N-heterocyclic carbene complex

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