Luminescence studies of the intracellular distribution of a dinuclear gold(I) N-heterocyclic carbene complex

Peter J. Barnard*, Louise E. Wedlock, Murray V. Baker, Susan J. Berners-Price, David A. Joyce, Brian W. Skelton, James H. Steer

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

212 Citations (Scopus)

Abstract

(Figure Presented) Gold lights the way: A bidentate cyclophane N-heterocyclic carbene ligand has been used to synthesize a new dinuclear AuI complex of the formula [Au2L2] 2+. The short Au⋯Au distance imposed by the rigid cyclophane ligand leads to a red-shifted luminescence profile that enables the complex to be used as a luminescent probe for distribution studies in single living cancer cells.

Original languageEnglish
Pages (from-to)5966-5970
Number of pages5
JournalAngewandte Chemie - International Edition
Volume45
Issue number36
DOIs
Publication statusPublished - 11 Sep 2006
Externally publishedYes

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