Lumped parameter model of cardiovascular-respiratory interaction

Fabrizio Gaudenzi, Alberto P. Avolio

    Research output: Chapter in Book/Report/Conference proceedingConference proceeding contributionpeer-review

    4 Citations (Scopus)

    Abstract

    The aim of this work was to develop a lumped parameter model of the cardiovascular system and to couple it with a model of respiratory mechanics. In comparison to existing models, modifications and additions have been implemented to include a model of the upper limb vasculature employing the electrical analogy of hemodynamic variables. The model prediction of respiratory effects on arterial pressure was compared with in vivo invasive measurement of blood pressure in patients. The model indicates that the inherent coupling between the cardiovascular and respiratory systems can be described by mathematical relationships of physiological parameters with robust predictions. With specification of parameters based on individual measurements of cardio-respiratory variables, the model can be used in the clinical setting of intensive care units to predict hemodynamic changes and to optimize ventilation and volume loading strategies.

    Original languageEnglish
    Title of host publicationProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
    Place of PublicationPiscataway, NJ
    PublisherInstitute of Electrical and Electronics Engineers (IEEE)
    Pages473-476
    Number of pages4
    Volume2013
    ISBN (Print)9781457702167
    DOIs
    Publication statusPublished - 2013
    Event2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013 - Osaka, Japan
    Duration: 3 Jul 20137 Jul 2013

    Other

    Other2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013
    CountryJapan
    CityOsaka
    Period3/07/137/07/13

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