Macrogonadotropinoma, a venous thromboembolic event and asymptomatic extensive periventricular white matter changes in a patient with Klinefelter syndrome

Divya Namboodiri*, Hui Yi Ng, Aakansha Zala, John Magnussen, Andrew Davidson, Bernard Champion, Veronica Preda

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

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Abstract

Gonadotropinoma in Klinefelter syndrome (KS) is uncommon and may be a result of protracted stimulation of gonadotrophs from lack of androgen feedback. Associations of white matter changes and increased venous thromboembolic risk have been reported and need to be considered in patients with KS.

Original languageEnglish
Pages (from-to)675-679
Number of pages5
JournalClinical Case Reports
Volume8
Issue number4
Early online date4 Mar 2020
DOIs
Publication statusPublished - Apr 2020

Bibliographical note

Copyright the Author(s) 2020. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.

Keywords

  • Klinefelter syndrome
  • macrogonadotropinoma
  • periventricular white matter changes
  • pulmonary embolism
  • venous thromboembolism

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