Magnetohydrodynamic blood flow in patients with coronary artery disease

Ashkan Javadzadegan, Abouzar Moshfegh, Hamid Hassanzadeh Afrouzi, Mohammad Omidi

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Objectives: We aim to investigate the effect of a magnetic field with varying intensities on haemodynamic perturbations in a cohort of patients with coronary artery disease. Methods: Transient computational fluid dynamics (CFD) simulations were performed in three-dimensional (3D) models of coronary arteries reconstructed from 3D quantitative coronary angiography. The effect of magnetic field on wall shear stress (WSS) derived parameters including maximum wall shear stress (MWSS) and size of regions with low wall shear stress (ALWSS) as well as length of flow recirculation zones were determined. Results: The results showed a substantial reduction in MWSS, ALWSS and length of flow recirculation zones in the presence of magnetic field, in particular for coronaries with moderate to severe stenoses. When the whole cohort examined, time-averaged wall shear stress (TAWSS), ALWSS and the length of flow recirculation zones in the absence of magnetic field were approximately 1.71, 4.69 and 8.46 times greater than those in the presence of magnetic field, respectively. Conclusion: Our findings imply that an externally applied magnetic field can improve haemodynamic perturbations in human coronary arteries.

LanguageEnglish
Pages111-122
Number of pages12
JournalComputer Methods and Programs in Biomedicine
Volume163
DOIs
Publication statusPublished - 1 Sep 2018

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Magnetic Fields
Magnetohydrodynamics
Coronary Artery Disease
Blood
Shear stress
Magnetic fields
Hemodynamics
Coronary Vessels
Angiography
Hydrodynamics
Coronary Angiography
Pathologic Constriction
Computational fluid dynamics
Computer simulation

Keywords

  • Atherosclerosis
  • Coronary artery
  • Haemodynamic perturbations
  • Magnetic field

Cite this

Javadzadegan, Ashkan ; Moshfegh, Abouzar ; Afrouzi, Hamid Hassanzadeh ; Omidi, Mohammad. / Magnetohydrodynamic blood flow in patients with coronary artery disease. In: Computer Methods and Programs in Biomedicine. 2018 ; Vol. 163. pp. 111-122.
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Magnetohydrodynamic blood flow in patients with coronary artery disease. / Javadzadegan, Ashkan; Moshfegh, Abouzar; Afrouzi, Hamid Hassanzadeh; Omidi, Mohammad.

In: Computer Methods and Programs in Biomedicine, Vol. 163, 01.09.2018, p. 111-122.

Research output: Contribution to journalArticleResearchpeer-review

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