Magnetohydrodynamic blood flow in patients with coronary artery disease

Ashkan Javadzadegan*, Abouzar Moshfegh, Hamid Hassanzadeh Afrouzi, Mohammad Omidi

*Corresponding author for this work

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Objectives: We aim to investigate the effect of a magnetic field with varying intensities on haemodynamic perturbations in a cohort of patients with coronary artery disease. Methods: Transient computational fluid dynamics (CFD) simulations were performed in three-dimensional (3D) models of coronary arteries reconstructed from 3D quantitative coronary angiography. The effect of magnetic field on wall shear stress (WSS) derived parameters including maximum wall shear stress (MWSS) and size of regions with low wall shear stress (ALWSS) as well as length of flow recirculation zones were determined. Results: The results showed a substantial reduction in MWSS, ALWSS and length of flow recirculation zones in the presence of magnetic field, in particular for coronaries with moderate to severe stenoses. When the whole cohort examined, time-averaged wall shear stress (TAWSS), ALWSS and the length of flow recirculation zones in the absence of magnetic field were approximately 1.71, 4.69 and 8.46 times greater than those in the presence of magnetic field, respectively. Conclusion: Our findings imply that an externally applied magnetic field can improve haemodynamic perturbations in human coronary arteries.

Original languageEnglish
Pages (from-to)111-122
Number of pages12
JournalComputer Methods and Programs in Biomedicine
Volume163
DOIs
Publication statusPublished - 1 Sep 2018

Keywords

  • Atherosclerosis
  • Coronary artery
  • Haemodynamic perturbations
  • Magnetic field

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