Management of bladder neck stenosis and urethral stricture and stenosis following treatment for prostate cancer

Helen L. Nicholson, Yasser Al-Hakeem, Javier J. Maldonado, Vincent Tse

Research output: Contribution to journalReview articleResearchpeer-review

Abstract

The aim of this review is to examine all urethral strictures and stenoses subsequent to treatment for prostate cancer, including radical prostatectomy (RP), radiotherapy, high intensity focused ultrasound (HIFU) and cryotherapy. The overall majority respond to endoscopic treatment, including dilatation, direct visual internal urethrotomy (DVIU) or bladder neck incision (BNI). There are adjunct treatments to endoscopic management, including injections of corticosteroids and mitomycin C (MMC) and urethral stents, which remain controversial and are not currently mainstay of treatment. Recalcitrant strictures are most commonly managed with urethroplasty, while recalcitrant stenosis is relatively rare yet almost always associated with bothersome urinary incontinence, requiring bladder neck reconstruction and subsequent artificial urinary sphincter (AUS) implantation, or urinary diversion for the devastated outlet.

LanguageEnglish
PagesS92-S102
Number of pages11
JournalTranslational Andrology and Urology
Volume6
Issue numberSuppl 2
DOIs
Publication statusPublished - 1 Jul 2017

Fingerprint

Urethral Stricture
Prostatic Neoplasms
Pathologic Constriction
Urinary Bladder
Artificial Urinary Sphincter
Urinary Diversion
Cryotherapy
Urinary Incontinence
Mitomycin
Therapeutics
Prostatectomy
Stents
Dilatation
Adrenal Cortex Hormones
Radiotherapy
Injections

Keywords

  • Bladder neck stenosis
  • Prostate cancer
  • Urethral stenosis
  • Urethral stricture

Cite this

Nicholson, Helen L. ; Al-Hakeem, Yasser ; Maldonado, Javier J. ; Tse, Vincent. / Management of bladder neck stenosis and urethral stricture and stenosis following treatment for prostate cancer. In: Translational Andrology and Urology. 2017 ; Vol. 6, No. Suppl 2. pp. S92-S102.
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Management of bladder neck stenosis and urethral stricture and stenosis following treatment for prostate cancer. / Nicholson, Helen L.; Al-Hakeem, Yasser; Maldonado, Javier J.; Tse, Vincent.

In: Translational Andrology and Urology, Vol. 6, No. Suppl 2, 01.07.2017, p. S92-S102.

Research output: Contribution to journalReview articleResearchpeer-review

TY - JOUR

T1 - Management of bladder neck stenosis and urethral stricture and stenosis following treatment for prostate cancer

AU - Nicholson, Helen L.

AU - Al-Hakeem, Yasser

AU - Maldonado, Javier J.

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AB - The aim of this review is to examine all urethral strictures and stenoses subsequent to treatment for prostate cancer, including radical prostatectomy (RP), radiotherapy, high intensity focused ultrasound (HIFU) and cryotherapy. The overall majority respond to endoscopic treatment, including dilatation, direct visual internal urethrotomy (DVIU) or bladder neck incision (BNI). There are adjunct treatments to endoscopic management, including injections of corticosteroids and mitomycin C (MMC) and urethral stents, which remain controversial and are not currently mainstay of treatment. Recalcitrant strictures are most commonly managed with urethroplasty, while recalcitrant stenosis is relatively rare yet almost always associated with bothersome urinary incontinence, requiring bladder neck reconstruction and subsequent artificial urinary sphincter (AUS) implantation, or urinary diversion for the devastated outlet.

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