Management of recurrent haemoptysis in malignancy with combined TISSEEL and intrabronchial valves

James Di Michiel, Corinna Pan, Alvin Ing, Tajalli Saghaie

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Management of recurrent haemoptysis poses a difficult clinical scenario. TISSEEL (Baxter Healthcare Corporation Deerfield, IL, USA) is a fibrin sealant often used in surgery to aid control of bleeding. However, when endoscopic TISSEEL is used independently, migration, dislodgement, or even expectoration of the fibrin clot is a common complication that may lead to recurrence of haemoptysis. Here we describe two patients with recurrent haemoptysis in the context of malignancy who underwent bronchoscopy, during which they were managed with application of topical TISSEEL to the bleeding area, followed by deployment of an intrabronchial valve, followed by a further application of TISSEEL over the valve. The combination of TISSEEL and intrabronchial valve appeared to control haemoptysis and was resistant to expectoration or migration in these two cases. Thus, this combination may provide a safe and effective therapeutic option for the control of bronchial bleeding secondary to malignancy.

LanguageEnglish
Article numbere00406
Pages1-3
Number of pages3
JournalRespirology Case Reports
Volume7
Issue number3
DOIs
Publication statusPublished - 1 Apr 2019

Fingerprint

Hemoptysis
Hemorrhage
Neoplasms
Fibrin Tissue Adhesive
Bronchoscopy
Fibrin
Delivery of Health Care
Recurrence
Therapeutics

Bibliographical note

Copyright the Author(s) 2019. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.

Keywords

  • Bronchoscopy
  • endobronchial valves
  • fibrin sealant
  • haemoptysis
  • malignancy

Cite this

Di Michiel, James ; Pan, Corinna ; Ing, Alvin ; Saghaie, Tajalli. / Management of recurrent haemoptysis in malignancy with combined TISSEEL and intrabronchial valves. In: Respirology Case Reports. 2019 ; Vol. 7, No. 3. pp. 1-3.
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Management of recurrent haemoptysis in malignancy with combined TISSEEL and intrabronchial valves. / Di Michiel, James; Pan, Corinna; Ing, Alvin; Saghaie, Tajalli.

In: Respirology Case Reports, Vol. 7, No. 3, e00406, 01.04.2019, p. 1-3.

Research output: Contribution to journalArticleResearchpeer-review

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