Hjerneskademarkøren S100B kan mindske brugen af computertomografi ved lette hovedtraumer - sekundærpublikation

Translated title of the contribution: Managing patients with minor head injury with a simple blood test - secondary publication

Jacob Bertram Springborg*, Johan Undén, Tor Ingebrigtsen, Bertil Romner

*Corresponding author for this work

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

The risk of acute intracranial complications after minor head injury (MHI) is low. Despite this, computed tomography (CT) is generally recommended with clinical observation as a secondary option. Both options have disadvantages. Clinical studies have shown the potential advantages of using the biomarker S100B. The specificity of S100B is low, but a high sensitivity for brain damage results in a clinically useful, high negative predictive value (NPV). Integration of S100B into existing management routines can reduce the need for CT scans or admission by over 30%.

Original languageDanish
Pages (from-to)978-981
Number of pages4
JournalUgeskrift for Laeger
Volume171
Issue number12
Publication statusPublished - Mar 2009
Externally publishedYes

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