Mapping the distribution of the telomeric sequence (T2AG 3)n in the Macropodoidea (Marsupialia) by fluorescence in situ hybridization. II. The ancestral 2n = 22 macropodid karyotype

C. J. Metcalfe; M. D. B. Eldridge; P. G. Johnston

doi:10.1159/000098189

Mapping the distribution of the telomeric sequence (T₂AG ₃)_n in the Macropodoidea (Marsupialia) by fluorescence in situ hybridization. II. The ancestral 2n = 22 macropodid karyotype

C. J. Metcalfe^*, M. D. B. Eldridge, P. G. Johnston

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

24 Citations (Scopus)

Abstract

In marsupial karyotypes with little heterochromatin, the telomeric sequence (T₂AG₃)_n, is involved in chromosome rearrangements. Here we compare the distribution of the (T₂AG ₃)_n sequence in chromosomes recently derived by fusions and other rearrangements (7-0.5 MYBP) with its distribution in chromosomes derived earlier (24-9 MYBP). We have previously shown that the (T ₂AG₃)_n sequence is consistently retained during chromosome rearrangements that are recent (7-0.5 MYBP). We suggest that in less recent rearrangements (24-9 MYBP) the pattern observed is initial retention followed by loss or amplification. We also suggest that the presence of interstitial (T₂AG₃)_n sequence is related to the evolutionary status of single chromosomes rather than entire karyotypes.

Original language	English
Pages (from-to)	212-217
Number of pages	6
Journal	Cytogenetic and Genome Research
Volume	116
Issue number	3
DOIs	https://doi.org/10.1159/000098189
Publication status	Published - Feb 2007

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title = "Mapping the distribution of the telomeric sequence (T2AG 3)n in the Macropodoidea (Marsupialia) by fluorescence in situ hybridization. II. The ancestral 2n = 22 macropodid karyotype",

abstract = "In marsupial karyotypes with little heterochromatin, the telomeric sequence (T2AG3)n, is involved in chromosome rearrangements. Here we compare the distribution of the (T2AG 3)n sequence in chromosomes recently derived by fusions and other rearrangements (7-0.5 MYBP) with its distribution in chromosomes derived earlier (24-9 MYBP). We have previously shown that the (T 2AG3)n sequence is consistently retained during chromosome rearrangements that are recent (7-0.5 MYBP). We suggest that in less recent rearrangements (24-9 MYBP) the pattern observed is initial retention followed by loss or amplification. We also suggest that the presence of interstitial (T2AG3)n sequence is related to the evolutionary status of single chromosomes rather than entire karyotypes.",

author = "Metcalfe, {C. J.} and Eldridge, {M. D. B.} and Johnston, {P. G.}",

year = "2007",

month = feb,

doi = "10.1159/000098189",

language = "English",

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pages = "212--217",

journal = "Cytogenetic and Genome Research",

issn = "1424-8581",

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}

Mapping the distribution of the telomeric sequence (T₂AG ₃)_n in the Macropodoidea (Marsupialia) by fluorescence in situ hybridization. II. The ancestral 2n = 22 macropodid karyotype. / Metcalfe, C. J.; Eldridge, M. D. B.; Johnston, P. G.
In: Cytogenetic and Genome Research, Vol. 116, No. 3, 02.2007, p. 212-217.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Mapping the distribution of the telomeric sequence (T2AG 3)n in the Macropodoidea (Marsupialia) by fluorescence in situ hybridization. II. The ancestral 2n = 22 macropodid karyotype

AU - Metcalfe, C. J.

AU - Eldridge, M. D. B.

AU - Johnston, P. G.

PY - 2007/2

Y1 - 2007/2

N2 - In marsupial karyotypes with little heterochromatin, the telomeric sequence (T2AG3)n, is involved in chromosome rearrangements. Here we compare the distribution of the (T2AG 3)n sequence in chromosomes recently derived by fusions and other rearrangements (7-0.5 MYBP) with its distribution in chromosomes derived earlier (24-9 MYBP). We have previously shown that the (T 2AG3)n sequence is consistently retained during chromosome rearrangements that are recent (7-0.5 MYBP). We suggest that in less recent rearrangements (24-9 MYBP) the pattern observed is initial retention followed by loss or amplification. We also suggest that the presence of interstitial (T2AG3)n sequence is related to the evolutionary status of single chromosomes rather than entire karyotypes.

AB - In marsupial karyotypes with little heterochromatin, the telomeric sequence (T2AG3)n, is involved in chromosome rearrangements. Here we compare the distribution of the (T2AG 3)n sequence in chromosomes recently derived by fusions and other rearrangements (7-0.5 MYBP) with its distribution in chromosomes derived earlier (24-9 MYBP). We have previously shown that the (T 2AG3)n sequence is consistently retained during chromosome rearrangements that are recent (7-0.5 MYBP). We suggest that in less recent rearrangements (24-9 MYBP) the pattern observed is initial retention followed by loss or amplification. We also suggest that the presence of interstitial (T2AG3)n sequence is related to the evolutionary status of single chromosomes rather than entire karyotypes.

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U2 - 10.1159/000098189

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SN - 1424-8581

VL - 116

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EP - 217

JO - Cytogenetic and Genome Research

JF - Cytogenetic and Genome Research

IS - 3

ER -

Mapping the distribution of the telomeric sequence (T₂AG ₃)_n in the Macropodoidea (Marsupialia) by fluorescence in situ hybridization. II. The ancestral 2n = 22 macropodid karyotype

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