Mapping the distribution of the telomeric sequence (T2AG 3)n in the Macropodoidea (Marsupialia) by fluorescence in situ hybridization. II. The ancestral 2n = 22 macropodid karyotype

C. J. Metcalfe*, M. D. B. Eldridge, P. G. Johnston

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    22 Citations (Scopus)

    Abstract

    In marsupial karyotypes with little heterochromatin, the telomeric sequence (T2AG3)n, is involved in chromosome rearrangements. Here we compare the distribution of the (T2AG 3)n sequence in chromosomes recently derived by fusions and other rearrangements (7-0.5 MYBP) with its distribution in chromosomes derived earlier (24-9 MYBP). We have previously shown that the (T 2AG3)n sequence is consistently retained during chromosome rearrangements that are recent (7-0.5 MYBP). We suggest that in less recent rearrangements (24-9 MYBP) the pattern observed is initial retention followed by loss or amplification. We also suggest that the presence of interstitial (T2AG3)n sequence is related to the evolutionary status of single chromosomes rather than entire karyotypes.

    Original languageEnglish
    Pages (from-to)212-217
    Number of pages6
    JournalCytogenetic and Genome Research
    Volume116
    Issue number3
    DOIs
    Publication statusPublished - Feb 2007

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