Matrix metalloproteinases and their inhibitors in bone remodelling following distraction osteogenesis of the sheep mandible

D. D. Marucci; Y Yu; James McTavish; F Bonar; M. Poole; W Walsh

Matrix metalloproteinases and their inhibitors in bone remodelling following distraction osteogenesis of the sheep mandible

D. D. Marucci, Y Yu, James McTavish, F Bonar, M. Poole, W Walsh

Faculty of Medicine, Health and Human Sciences

Research output: Chapter in Book/Report/Conference proceeding › Conference proceeding contribution › peer-review

Abstract

Matrix Metalloproteinases (MMPs) and Tissue Inhibitors of MMPS (TIMPs) are important in bony remodelling following mandibular lengthening by distraction osteogenesis and can be used to assess bone metabolic activity related to remodelling. By 12 months following distraction levels, of MMP and TIMP activity are comparable to those in undistracted bone, suggesting that bone remodelling is complete. This further supports the assertion that there is no bony relapse following distraction osteogenesis in the sheep mandible, particularly at late time-points and that the regenerate bone at this time is stable.

Original language	English
Title of host publication	3rd International Congress on Cranial and Facial Bone Distraction Processes
Editors	E Arnaud, PA Diner
Place of Publication	Bologna, Italy
Publisher	Monduzzi Editore
Pages	23-25
Number of pages	3
ISBN (Print)	8832316145
Publication status	Published - 2001
Event	3rd International Congress of Craniofacial and Maxillofacial Distraction - PARIS, France Duration: 14 Jun 2001 → 16 Jun 2001

Conference

Conference	3rd International Congress of Craniofacial and Maxillofacial Distraction
Country/Territory	France
City	PARIS
Period	14/06/01 → 16/06/01

Keywords

TIMP-1

Cite this

@inproceedings{2f6c1e9119a1445193607e660c09c658,

title = "Matrix metalloproteinases and their inhibitors in bone remodelling following distraction osteogenesis of the sheep mandible",

abstract = "Matrix Metalloproteinases (MMPs) and Tissue Inhibitors of MMPS (TIMPs) are important in bony remodelling following mandibular lengthening by distraction osteogenesis and can be used to assess bone metabolic activity related to remodelling. By 12 months following distraction levels, of MMP and TIMP activity are comparable to those in undistracted bone, suggesting that bone remodelling is complete. This further supports the assertion that there is no bony relapse following distraction osteogenesis in the sheep mandible, particularly at late time-points and that the regenerate bone at this time is stable.",

keywords = "TIMP-1",

author = "Marucci, {D. D.} and Y Yu and James McTavish and F Bonar and M. Poole and W Walsh",

year = "2001",

language = "English",

isbn = "8832316145",

pages = "23--25",

editor = "E Arnaud and PA Diner",

booktitle = "3rd International Congress on Cranial and Facial Bone Distraction Processes",

publisher = "Monduzzi Editore",

note = "3rd International Congress of Craniofacial and Maxillofacial Distraction ; Conference date: 14-06-2001 Through 16-06-2001",

}

Marucci, DD, Yu, Y, McTavish, J, Bonar, F, Poole, M & Walsh, W 2001, Matrix metalloproteinases and their inhibitors in bone remodelling following distraction osteogenesis of the sheep mandible. in E Arnaud & PA Diner (eds), 3rd International Congress on Cranial and Facial Bone Distraction Processes. Monduzzi Editore, Bologna, Italy, pp. 23-25, 3rd International Congress of Craniofacial and Maxillofacial Distraction, PARIS, France, 14/06/01.

Matrix metalloproteinases and their inhibitors in bone remodelling following distraction osteogenesis of the sheep mandible. / Marucci, D. D.; Yu, Y; McTavish, James et al.

3rd International Congress on Cranial and Facial Bone Distraction Processes. ed. / E Arnaud; PA Diner. Bologna, Italy : Monduzzi Editore, 2001. p. 23-25.

Research output: Chapter in Book/Report/Conference proceeding › Conference proceeding contribution › peer-review

TY - GEN

T1 - Matrix metalloproteinases and their inhibitors in bone remodelling following distraction osteogenesis of the sheep mandible

AU - Marucci, D. D.

AU - Yu, Y

AU - McTavish, James

AU - Bonar, F

AU - Poole, M.

AU - Walsh, W

PY - 2001

Y1 - 2001

N2 - Matrix Metalloproteinases (MMPs) and Tissue Inhibitors of MMPS (TIMPs) are important in bony remodelling following mandibular lengthening by distraction osteogenesis and can be used to assess bone metabolic activity related to remodelling. By 12 months following distraction levels, of MMP and TIMP activity are comparable to those in undistracted bone, suggesting that bone remodelling is complete. This further supports the assertion that there is no bony relapse following distraction osteogenesis in the sheep mandible, particularly at late time-points and that the regenerate bone at this time is stable.

AB - Matrix Metalloproteinases (MMPs) and Tissue Inhibitors of MMPS (TIMPs) are important in bony remodelling following mandibular lengthening by distraction osteogenesis and can be used to assess bone metabolic activity related to remodelling. By 12 months following distraction levels, of MMP and TIMP activity are comparable to those in undistracted bone, suggesting that bone remodelling is complete. This further supports the assertion that there is no bony relapse following distraction osteogenesis in the sheep mandible, particularly at late time-points and that the regenerate bone at this time is stable.

KW - TIMP-1

M3 - Conference proceeding contribution

SN - 8832316145

SP - 23

EP - 25

BT - 3rd International Congress on Cranial and Facial Bone Distraction Processes

A2 - Arnaud, E

A2 - Diner, PA

PB - Monduzzi Editore

CY - Bologna, Italy

T2 - 3rd International Congress of Craniofacial and Maxillofacial Distraction

Y2 - 14 June 2001 through 16 June 2001

ER -

Matrix metalloproteinases and their inhibitors in bone remodelling following distraction osteogenesis of the sheep mandible

Abstract

Conference

Keywords

Fingerprint

Cite this