Abstract
To test the hypothesis that latency delay in the fellow eyes of optic neuritis (ON) patients and to compensate for delayed transmission of visual information, latency change of multi-focal visual evoked potential (mfVEP) traces in fellow eyes of 15 ON patients were analyzed. Patients with low risk (LR) for developing multiple sclerosis (MS) were examined separately from MS patients to isolate effect of cortical plasticity from potential pathological changes in disseminated disease. The small increase in latency in fellow eyes of LR group was statistically not significant. In MS patients, the latency was significantly delayed (P<0.02). The magnitude of the latency change in the fellow eyes did not correlate with the severity of latency delay in the affected eyes (R2<0.02, P=0.3). The differences between ON patients with and without MS, reported here, suggest that the presence of disseminated disease plays critical role in latency delay of the fellow eye.
| Language | English |
|---|---|
| Pages | 329-332 |
| Number of pages | 4 |
| Journal | International Journal of Ophthalmology |
| Volume | 11 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 1 Jan 2018 |
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Keywords
- Fellow eyes
- Latency delay
- Multi-focal visual evoked potential
- Optic neuritis
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Mechanism of delayed conduction of fellow eyes in patients with optic neuritis. / Alshowaeir, Daniah; Yiannikas, Con; Fraser, Clare; Klistorner, Alexander.
In: International Journal of Ophthalmology, Vol. 11, No. 2, 01.01.2018, p. 329-332.Research output: Contribution to journal › Article › Research › peer-review
TY - JOUR
T1 - Mechanism of delayed conduction of fellow eyes in patients with optic neuritis
AU - Alshowaeir, Daniah
AU - Yiannikas, Con
AU - Fraser, Clare
AU - Klistorner, Alexander
PY - 2018/1/1
Y1 - 2018/1/1
N2 - To test the hypothesis that latency delay in the fellow eyes of optic neuritis (ON) patients and to compensate for delayed transmission of visual information, latency change of multi-focal visual evoked potential (mfVEP) traces in fellow eyes of 15 ON patients were analyzed. Patients with low risk (LR) for developing multiple sclerosis (MS) were examined separately from MS patients to isolate effect of cortical plasticity from potential pathological changes in disseminated disease. The small increase in latency in fellow eyes of LR group was statistically not significant. In MS patients, the latency was significantly delayed (P<0.02). The magnitude of the latency change in the fellow eyes did not correlate with the severity of latency delay in the affected eyes (R2<0.02, P=0.3). The differences between ON patients with and without MS, reported here, suggest that the presence of disseminated disease plays critical role in latency delay of the fellow eye.
AB - To test the hypothesis that latency delay in the fellow eyes of optic neuritis (ON) patients and to compensate for delayed transmission of visual information, latency change of multi-focal visual evoked potential (mfVEP) traces in fellow eyes of 15 ON patients were analyzed. Patients with low risk (LR) for developing multiple sclerosis (MS) were examined separately from MS patients to isolate effect of cortical plasticity from potential pathological changes in disseminated disease. The small increase in latency in fellow eyes of LR group was statistically not significant. In MS patients, the latency was significantly delayed (P<0.02). The magnitude of the latency change in the fellow eyes did not correlate with the severity of latency delay in the affected eyes (R2<0.02, P=0.3). The differences between ON patients with and without MS, reported here, suggest that the presence of disseminated disease plays critical role in latency delay of the fellow eye.
KW - Fellow eyes
KW - Latency delay
KW - Multi-focal visual evoked potential
KW - Optic neuritis
UR - http://www.scopus.com/inward/record.url?scp=85044282708&partnerID=8YFLogxK
U2 - 10.18240/ijo.2018.02.24
DO - 10.18240/ijo.2018.02.24
M3 - Article
VL - 11
SP - 329
EP - 332
JO - International Journal of Ophthalmology
T2 - International Journal of Ophthalmology
JF - International Journal of Ophthalmology
SN - 2222-3959
IS - 2
ER -