Membrane proteins and proteomics: Un amour impossible?

Véronique Santoni, Mark Molloy, Thierry Rabilloud*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

820 Citations (Scopus)

Abstract

Proteome analysis implies the ability to separate proteins as a first step prior to characterization. Thus, the overall performance of the analysis strongly depends on the performance of the separation tool, usually two- dimensional electrophoresis. This review shows how two-dimensional electrophoresis performs with membrane proteins from bacteria or animal or vegetable cells and tissues, the recent progress in this field, and it examines future prospects in this area.

Original languageEnglish
Pages (from-to)1054-1070
Number of pages17
JournalElectrophoresis
Volume21
Issue number6
DOIs
Publication statusPublished - 2000
Externally publishedYes

Keywords

  • Membrane proteins
  • Proteomics
  • Review

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